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Global Health: Science and Practice
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Global Health: Science and Practice

Dedicated to what works in global health programs

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Tuberculosis

  • Open Access
    How Do Private Providers Unaffiliated With the Nigeria National TB Program Diagnose and Treat Drug-Susceptible TB Patients? A Cross-Sectional Study
    Victor Abiola Adepoju, Ademola Adelekan, Victoria Etuk, Moses Onoh and Babatunde Olofinbiyi
    Global Health: Science and Practice December 2022, 10(6):e2200210; https://doi.org/10.9745/GHSP-D-22-00210

    Private providers unaffiliated with the National TB Program (NTP) in Nigeria are not diagnosing or treating drug-susceptible TB patients according to NTP guidelines, resulting in an urgent need to engage non-NTP providers and improve the quality of their TB services.

  • Open Access
    Crossing the Last Mile of TB Care in Rural Southern Madagascar: A Multistakeholder Initiative
    Nadine Muller, Fierenantsoa Ranjaharinony, Miandrisoa Etrahagnane, Anna Frühauf, Turibio Razafindranaivo, Hortensia Ramasimanana and Julius Valentin Emmrich
    Global Health: Science and Practice October 2022, 10(5):e2200101; https://doi.org/10.9745/GHSP-D-22-00101

    Decentralizing TB care services by offering motorbike-based mobile clinics increased patient accessibility to TB care services in a remote district in Madagascar.

  • Open Access
    Screening for Severe Illness at Diagnosis Has the Potential to Prevent Early TB Deaths: Programmatic Experience From Karnataka, India
    Hemant Deepak Shewade, Sharath Burugina Nagaraja, Basavarajachar Vanitha, Hosadurga Jagadish Deepak Murthy, Madhavi Bhargava, Anil Singarajipura, Suresh G. Shastri, Bharatkumar Hargovandas Patel, Kajal Davara, Ramesh Chandra Reddy, Ajay M.V. Kumar and Anurag Bhargava
    Global Health: Science and Practice August 2022, 10(4):e2100736; https://doi.org/10.9745/GHSP-D-21-00736

    Despite TB being a potentially fatal disease, severity is not systematically assessed at the start of drug-susceptible TB treatment. We document our experience screening people for severe illness at diagnosis/notification in program settings and the potential impact on reducing early TB deaths.

  • Open Access
    Uganda Public Health Fellowship Program's Contributions to the National HIV and TB Programs, 2015–2020
    Alex R. Ario, Lilian Bulage, Yvette Wibabara, Peter Muwereza, Daniel Eurien, Steven N. Kabwama, Benon Kwesiga, Daniel Kadobera, Stavia Turyahabwe, Joshua B. Musinguzi, Rhoda K. Wanyenze, Pamela M. Nasirumbi, Deus Lukoye, Julie R. Harris, Lisa A. Mills and Lisa J. Nelson
    Global Health: Science and Practice April 2022, 10(2):e2100574; https://doi.org/10.9745/GHSP-D-21-00574

    The Uganda Public Health Fellowship Program has built the capacity of its fellows to address multiple gaps in the Uganda health system as well as to contribute to improving Uganda's ability to prevent, prepare for, and respond to public health emergencies such as HIV and TB.

  • Open Access
    Leveraging Experience From Active TB Drug-Safety Monitoring and Management for Monitoring Active Antiretroviral Toxicity
    Lisa Stevens, Kelly E. Perry, Iakuna Moide, Francil Kaemala, Justine Nankinga, Anh L. Innes and Ignatius Mogaba
    Global Health: Science and Practice April 2022, 10(2):e2100595; https://doi.org/10.9745/GHSP-D-21-00595

    Systems established for active drug safety monitoring and management of drug-resistant TB should be leveraged to ensure comprehensive surveillance for active toxicity monitoring during scale-up of newer antiretroviral regimens.

  • Open Access
    Using a Pharmacy-Based Surveillance System to Improve Standards for TB Care in Kerala, India
    Rakesh PS, Shibu Balakrishnan, Rakesh Ramachandran, Smitha Nandhan, Nidhish Issac Samuel, Pramodkumar PP and Suja Aloysius
    Global Health: Science and Practice December 2021, 9(4):846-854; https://doi.org/10.9745/GHSP-D-21-00346

    A pharmacy-based surveillance system in Kerala, India, has helped to improve TB patient notifications from the private sector, build better public-private partnerships, and improve the quality of TB diagnosis. Pharmacy-based surveillance has the potential to strengthen TB surveillance and facilitate standards of TB care.

  • Open Access
    Lessons Learned During the COVID-19 Pandemic to Strengthen TB Infection Control: A Rapid Review
    Helena J. Chapman and Bienvenido A. Veras-Estévez
    Global Health: Science and Practice December 2021, 9(4):964-977; https://doi.org/10.9745/GHSP-D-21-00368

    In light of competing health priorities of COVID-19 and TB, we propose recommendations to strengthen health system preparedness for optimal TB control across low- and middle-income countries during and after the COVID-19 pandemic.

  • Open Access
    A Quality Improvement Intervention to Inform Scale-Up of Integrated HIV-TB Services: Lessons Learned From KwaZulu-Natal, South Africa
    Santhanalakshmi Gengiah, Kogieleum Naidoo, Regina Mlobeli, Maureen F. Tshabalala, Andrew J. Nunn, Nesri Padayatchi, Nonhlanhla Yende-Zuma, Myra Taylor, Pierre M. Barker and Marian Loveday
    Global Health: Science and Practice September 2021, 9(3):444-458; https://doi.org/10.9745/GHSP-D-21-00157

    Despite being standard of care, gaps in HIV-TB service delivery are present. Quality Improvement methods are effective in uncovering health systems weaknesses that impede efficient delivery of integrated HIV-TB services.

  • Open Access
    Implementation of GeneXpert for TB Testing in Low- and Middle-Income Countries: A Systematic Review
    Scott Brown, Justine E. Leavy and Jonine Jancey
    Global Health: Science and Practice September 2021, 9(3):698-710; https://doi.org/10.9745/GHSP-D-21-00121

    This review highlights a commonality of implementation barriers across geographically dispersed GeneXpert interventions for TB testing. This indicates the importance of using implementation frameworks to report findings that can improve public health outcomes across low- and middle-income countries.

  • Open Access
    STEPS: A Solution for Ensuring Standards of TB Care for Patients Reaching Private Hospitals in India
    Shibu Balakrishnan, Rakesh PS, Sunilkumar M, Bhavan Sankar, Rakesh Ramachandran, Ameer KA, Ramani Gopi and Prem Nair
    Global Health: Science and Practice June 2021, 9(2):286-295; https://doi.org/10.9745/GHSP-D-20-00449

    A low-cost model for engaging the private sector to address gaps in TB care and ensuring that patients in the private sector receive the standards of care in India was feasible. The pilot project showed improvements in standards of care, which benefits the patient, government, private hospitals, and society.

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