Infectious Diseases
- Novel Approaches to Postnatal Prophylaxis to Eliminate Vertical Transmission of HIV
Despite progress in providing antiretroviral therapy to pregnant women living with HIV, a substantial number of vertical transmissions continue to occur. Novel approaches leveraging modern potent, safe, and well-tolerated antiretroviral drugs are urgently needed.
- Toward Meaningful Cultural Adaptation Across Implementation Stages: Lessons Learned From a Culturally Based HIV Stigma Intervention in Gaborone, Botswana
A culturally based stigma intervention for pregnant women living with HIV in Gaborone, Botswana highlights the importance of conceptualizing and formalizing cultural adaptation across all stages of implementation.
- Preexposure Prophylaxis Among Pregnant and Lactating People in 18 PEPFAR-Supported Countries: A Review of HIV Strategies and Guidelines
The use of preexposure prophylaxis (PrEP) is a safe, efficacious method to prevent HIV infections among pregnant and lactating people (PLP) and their infants. Despite growing support for PrEP use among PLP and notable changes in national policies, many policy gaps persist.
- How Do Private Providers Unaffiliated With the Nigeria National TB Program Diagnose and Treat Drug-Susceptible TB Patients? A Cross-Sectional Study
Private providers unaffiliated with the National TB Program (NTP) in Nigeria are not diagnosing or treating drug-susceptible TB patients according to NTP guidelines, resulting in an urgent need to engage non-NTP providers and improve the quality of their TB services.
- Community Health Workers Improve HIV Disclosure Among HIV-Affected Sexual Partners in Rural Uganda: A Quasi-Experimental Study
HIV disclosure is critical to achieve positive HIV treatment and management outcomes. Community health worker–led mechanisms may be used to support disclosure among adults living with HIV in heterosexual relationships in rural settings.
- Bottlenecks and Solutions During Implementation of the DREAMS Program for Adolescent Girls and Young Women in Namibia
We analyze implementation bottlenecks experienced in the DREAMS program in Namibia that can provide valuable insights and suggest ways to anticipate and overcome these challenges when managing HIV and gender-based violence prevention programs for adolescent girls and young women.
- Multisectoral, Combination HIV Prevention for Adolescent Girls and Young Women: A Qualitative Study of the DREAMS Implementation Trajectory in Zambia
Our study of DREAMS implementation in Zambia identified key implementation successes and challenges experienced by implementing partners and program participants, from program rollout and throughout its evolution.
- Early Reflections on Mphatlalatsane, a Maternal and Neonatal Quality Improvement Initiative Implemented During COVID-19 in South Africa
A quality improvement initiative for maternal and neonatal health care demonstrates that a responsive intervention design and implementation approach mitigates threats to clinical services during COVID-19.
- Financial Implications of Tariffs for Medical Oxygen on Rwandan Public Hospitals’ Finance Management During the Coronavirus Epidemic
This study shows how variations in patient consumption of medical oxygen can be used to determine tariffs more accurately and highlights the need for a transition from the time-based tariff structure to a case-based or volume-based tariff to incentivize sustainable production of medical oxygen services at hospitals in Rwanda.
- Do Children With Congenital Zika Syndrome Have Cerebral Palsy?
As researchers and practitioners, we have an important role in educating families of children with brain damage caused by Zika virus infection on how a cerebral palsy diagnosis can empower them with more information and enable better access to care and intervention services.