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Global Health: Science and Practice
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Global Health: Science and Practice

Dedicated to what works in global health programs

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Infectious Diseases

  • Open Access
    Novel Approaches to Postnatal Prophylaxis to Eliminate Vertical Transmission of HIV
    Theodore Ruel, Martina Penazzato, Jennifer M. Zech, Moherndran Archary, Tim R. Cressey, Ameena Goga, Joseph Harwell, Raphael J. Landovitz, Maria Grazia Lain, Marc Lallemant, Eleanor Namusoke-Magongo, Irene Mukui, Sallie R. Permar, Andrew J. Prendergast, Roger Shapiro and Elaine J. Abrams
    Global Health: Science and Practice April 2023, 11(2):e2200401; https://doi.org/10.9745/GHSP-D-22-00401

    Despite progress in providing antiretroviral therapy to pregnant women living with HIV, a substantial number of vertical transmissions continue to occur. Novel approaches leveraging modern potent, safe, and well-tolerated antiretroviral drugs are urgently needed.

  • Open Access
    Preexposure Prophylaxis Among Pregnant and Lactating People in 18 PEPFAR-Supported Countries: A Review of HIV Strategies and Guidelines
    Sheena Sharifi Abadan, Liz Hawryluk, Michele Montandon, Nicole Flowers, Jane Schueller, Robyn Eakle, Pragna Patel, Michelle S. Chevalier, Sangeeta Rana and Anouk Amzel
    Global Health: Science and Practice December 2022, 10(6):e2200129; https://doi.org/10.9745/GHSP-D-22-00129

    The use of preexposure prophylaxis (PrEP) is a safe, efficacious method to prevent HIV infections among pregnant and lactating people (PLP) and their infants. Despite growing support for PrEP use among PLP and notable changes in national policies, many policy gaps persist.

  • Open Access
    How Do Private Providers Unaffiliated With the Nigeria National TB Program Diagnose and Treat Drug-Susceptible TB Patients? A Cross-Sectional Study
    Victor Abiola Adepoju, Ademola Adelekan, Victoria Etuk, Moses Onoh and Babatunde Olofinbiyi
    Global Health: Science and Practice December 2022, 10(6):e2200210; https://doi.org/10.9745/GHSP-D-22-00210

    Private providers unaffiliated with the National TB Program (NTP) in Nigeria are not diagnosing or treating drug-susceptible TB patients according to NTP guidelines, resulting in an urgent need to engage non-NTP providers and improve the quality of their TB services.

  • Open Access
    Toward Meaningful Cultural Adaptation Across Implementation Stages: Lessons Learned From a Culturally Based HIV Stigma Intervention in Gaborone, Botswana
    Ohemaa B. Poku, Evan L. Eschliman, Rayna Y. Wang, Shathani Rampa, Haitisha Mehta, Patlo Entaile, Tingyu Li, Valerie W. Jackson, Ari Ho-Foster, Michael B. Blank and Lawrence H. Yang
    Global Health: Science and Practice December 2022, 10(6):e2200232; https://doi.org/10.9745/GHSP-D-22-00232

    A culturally based stigma intervention for pregnant women living with HIV in Gaborone, Botswana highlights the importance of conceptualizing and formalizing cultural adaptation across all stages of implementation.

  • Open Access
    Do Children With Congenital Zika Syndrome Have Cerebral Palsy?
    Alessandra Carvalho, Egmar Longo, Cristiana Nascimento-Carvalho, Nayara Argollo, Kátia Edni Coelho, Aline Sampaio, Carlos Brites and Rita Lucena
    Global Health: Science and Practice October 2022, 10(5):e2100575; https://doi.org/10.9745/GHSP-D-21-00575

    As researchers and practitioners, we have an important role in educating families of children with brain damage caused by Zika virus infection on how a cerebral palsy diagnosis can empower them with more information and enable better access to care and intervention services.

  • Open Access
    Crossing the Last Mile of TB Care in Rural Southern Madagascar: A Multistakeholder Initiative
    Nadine Muller, Fierenantsoa Ranjaharinony, Miandrisoa Etrahagnane, Anna Frühauf, Turibio Razafindranaivo, Hortensia Ramasimanana and Julius Valentin Emmrich
    Global Health: Science and Practice October 2022, 10(5):e2200101; https://doi.org/10.9745/GHSP-D-22-00101

    Decentralizing TB care services by offering motorbike-based mobile clinics increased patient accessibility to TB care services in a remote district in Madagascar.

  • Open Access
    Developing and Testing a Chatbot to Integrate HIV Education Into Family Planning Clinic Waiting Areas in Lusaka, Zambia
    Eileen A. Yam, Edith Namukonda, Tracy McClair, Samir Souidi, Nachela Chelwa, Nelly Muntalima, Michael Mbizvo and Ben Bellows
    Global Health: Science and Practice October 2022, 10(5):e2100721; https://doi.org/10.9745/GHSP-D-21-00721

    In response to the need to integrate HIV prevention content with FP counseling, a chatbot was developed and tested for use among FP clients in clinic waiting areas to leverage the time while they wait to see providers and guide them through a digital conversation on preventing both pregnancy and HIV.

  • Open Access
    Willingness to Pay for HIV Prevention Commodities Among Key Population Groups in Nigeria
    Olawale Durosinmi-Etti, Emmanuel Kelechi Nwala, Funke Oki, Akudo Ikpeazu, Emmanuel Godwin, Paul Umoh, Arome Shaibu, Alex Ogundipe and Abiye Kalaiwo
    Global Health: Science and Practice October 2022, 10(5):e2100303; https://doi.org/10.9745/GHSP-D-21-00303

    Exploring the willingness of certain population segments to pay for HIV commodities is the first step in developing strategies to maximize the use of free or subsidized products, increase access to products for key segments of the population, and ensure efficiency and sustainability of HIV prevention programming.

  • Open Access
    Community Health Workers Improve HIV Disclosure Among HIV-Affected Sexual Partners in Rural Uganda: A Quasi-Experimental Study
    Zubair Lukyamuzi, Ruth Mirembe Nabisere, Rita Nakalega, Patience Atuhaire, Hajira Kataike, Bashir Ssuna, Mazen Baroudi, Flavia Matovu Kiweewa, Philippa Musoke and Lisa M. Butler
    Global Health: Science and Practice October 2022, 10(5):e2100631; https://doi.org/10.9745/GHSP-D-21-00631

    HIV disclosure is critical to achieve positive HIV treatment and management outcomes. Community health worker–led mechanisms may be used to support disclosure among adults living with HIV in heterosexual relationships in rural settings.

  • Open Access
    Bottlenecks and Solutions During Implementation of the DREAMS Program for Adolescent Girls and Young Women in Namibia
    Ellen W. MacLachlan, Abigail K. Korn, Alison L. Ensminger, Sharon Zambwe, Theopolina Kueyo, Rosanne Kahuure, Gena Barnabee, Josua Nghipangelwa, Juliet Mudabeti, Prisca Tambo, Agnes Mwilima, Elizabeth Muremi, Norbert Forster, Christa Fischer-Walker and Gabrielle O’Malley
    Global Health: Science and Practice October 2022, 10(5):e2200226; https://doi.org/10.9745/GHSP-D-22-00226

    We analyze implementation bottlenecks experienced in the DREAMS program in Namibia that can provide valuable insights and suggest ways to anticipate and overcome these challenges when managing HIV and gender-based violence prevention programs for adolescent girls and young women.

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  • Cross-Cutting Topics
    • Adolescents and Youth (40)
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