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Global Health: Science and Practice
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Global Health: Science and Practice

Dedicated to what works in global health programs

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HIV/AIDS

  • Open Access
    Progress in Harmonizing Tiered HIV Laboratory Systems: Challenges and Opportunities in 8 African Countries
    Jason Williams, Farouk Umaru, Dianna Edgil and Joel Kuritsky
    Global Health: Science and Practice September 2016, 4(3):467-480; https://doi.org/10.9745/GHSP-D-16-00004

    Countries have had mixed results in adhering to laboratory instrument procurement lists, with some limiting instrument brand expansion and others experiencing substantial growth in instrument counts and brand diversity. Important challenges to advancing laboratory harmonization strategies include:

    1. Lack of adherence to procurement policies

    2. Lack of an effective coordinating body

    3. Misalignment of laboratory policies, treatment guidelines, and minimum service packages

  • Open Access
    Declining HIV Prevalence in Parallel With Safer Sex Behaviors in Burkina Faso: Evidence From Surveillance and Population-Based Surveys
    Fati Kirakoya-Samadoulougou, Nicolas Nagot, Sekou Samadoulougou, Mamadou Sokey, Abdoulaye Guiré, Issiaka Sombié and Nicolas Meda
    Global Health: Science and Practice June 2016, 4(2):326-335; https://doi.org/10.9745/GHSP-D-16-00013

    HIV prevalence among pregnant women ages 15–49 declined from 7.1% to 2.0% in urban areas between 1998 and 2014, and from 2.0% to 0.5% in rural areas between 2003 and 2014; similar declines were reported in the Demographic and Health Surveys. During the same time period, individuals reported safer sex behaviors, including delayed sexual debut and reduced number of sex partners among youth, as well as increased condom use at last sex with nonmarital partners among men and women ages 15–49.

  • Open Access
    The Single-Visit Approach as a Cervical Cancer Prevention Strategy Among Women With HIV in Ethiopia: Successes and Lessons Learned
    Netsanet Shiferaw, Graciela Salvador-Davila, Konjit Kassahun, Mohamad I Brooks, Teklu Weldegebreal, Yewondwossen Tilahun, Habtamu Zerihun, Tariku Nigatu, Kidest Lulu, Ismael Ahmed, Paul D Blumenthal and Mengistu Asnake
    Global Health: Science and Practice March 2016, 4(1):87-98; https://doi.org/10.9745/GHSP-D-15-00325

    With the single-visit approach for cervical cancer prevention, women with positive “visual inspection of the cervix with acetic acid wash” (VIA) test results receive immediate treatment of the precancerous lesion with cryotherapy. The approach worked successfully for women with HIV in Ethiopia in secondary and tertiary health facilities, with high screening and cryotherapy treatment rates. Sustainability and appropriate scale-up of such programs must address wider health system challenges including human resource constraints and shortage of essential supplies.

  • Open Access
    Reduced Effectiveness of Contraceptive Implants for Women Taking the Antiretroviral Efavirenz (EFV): Still Good Enough and for How Long?
    James D Shelton
    Global Health: Science and Practice December 2015, 3(4):528-531; https://doi.org/10.9745/GHSP-D-15-00356

    EFV clearly reduces effectiveness of implants. However, the reduced effectiveness still appears better compared with short-acting methods overall, at least for the initial period of implant use, and may be acceptable to many women. We need better data on effectiveness, especially over the long term and on whether ENG implants (Implanon) might be more effective than LNG implants (Jadelle). Communicating the risk of pregnancy to clients under these circumstances is very challenging. In the longer term, providing an alternative to EFV, such as dolutegravir, might solve this problem.

  • Open Access
    Sexual Satisfaction, Performance, and Partner Response Following Voluntary Medical Male Circumcision in Zambia: The Spear and Shield Project
    Robert Zulu, Deborah Jones, Ndashi Chitalu, Ryan Cook and Stephen Weiss
    Global Health: Science and Practice December 2015, 3(4):606-618; https://doi.org/10.9745/GHSP-D-15-00163

    Most men and their partners reported increased or the same levels of sexual pleasure and improved or no change in penile hygiene post-VMMC. While half of men reported increased or no change in sexual functioning (orgasm, erections), one-third reported a decrease. Early resumption of sexual intercourse prior to complete healing was most closely associated with adverse outcomes, including decreased sexual functioning, satisfaction, and desire.

  • Open Access
    Covering the Last Kilometer: Using GIS to Scale-Up Voluntary Medical Male Circumcision Services in Iringa and Njombe Regions, Tanzania
    Hally Mahler, Sarah Searle, Marya Plotkin, Yusuph Kulindwa, Seth Greenberg, Erick Mlanga, Emmanuel Njeuhmeli and Gissenje Lija
    Global Health: Science and Practice September 2015, 3(3):503-515; https://doi.org/10.9745/GHSP-D-15-00151

    Interactive GIS maps created by overlapping facility data including roads and infrastructure with population and service delivery data permitted strategic deployment of mobile voluntary medical male circumcision (VMMC) services to underserved rural communities. The percentage of VMMCs performed in rural areas jumped from 48% in 2011 to 93% in 2014.

  • Open Access
    Social Franchising: A Blockbuster to Address Unmet Need for Family Planning and to Advance Toward the FP2020 Goal
    Global Health: Science and Practice June 2015, 3(2):147-148; https://doi.org/10.9745/GHSP-D-15-00155

    Social franchising has scaled-up provision of voluntary family planning, especially long-acting reversible contraceptives, across Africa and Asia at a rapid and remarkable pace. The approach should be pursued vigorously, especially in countries with a significant private-sector presence, to advance the FP2020 goal of providing access to modern contraception to 120 million additional clients by 2020.

  • Open Access
    Toward a Systematic Approach to Generating Demand for Voluntary Medical Male Circumcision: Insights and Results From Field Studies
    Sema K Sgaier, James Baer, Daniel C Rutz, Emmanuel Njeuhmeli, Kim Seifert-Ahanda, Paulin Basinga, Rosie Parkyn and Catharine Laube
    Global Health: Science and Practice June 2015, 3(2):209-229; https://doi.org/10.9745/GHSP-D-15-00020

    Using an analytical framework to design and implement voluntary medical male circumcision (VMMC) programs can lead to more effective interventions, especially when insights are incorporated from disciplines such as behavioral science and commercial market research. Promising VMMC behavior change practices: (1) address individual, interpersonal, and environmental barriers and facilitators; (2) tailor messages to men’s behavior change stage and focus on other benefits besides HIV prevention, such as hygiene and sexual pleasure; (3) include women as a key target audience; (4) engage traditional and religious leaders; (5) use media to promote positive social norms; and (6) deploy community mobilizers to address individual concerns.

  • Open Access
    PEPFAR Transitions to Country Ownership: Review of Past Donor Transitions and Application of Lessons Learned to the Eastern Caribbean
    Abigail Vogus and Kylie Graff
    Global Health: Science and Practice June 2015, 3(2):274-286; https://doi.org/10.9745/GHSP-D-14-00227

    Six key steps for effective transition: (1) develop a roadmap; (2) involve stakeholders; (3) communicate the plan; (4) support midterm evaluations; (5) strengthen financial, technical, and management capacity; and (6) support ongoing M&E. The Eastern Caribbean will need to identify HIV champions; strengthen leadership and management; improve policies to protect key populations; engage the private sector and civil society more; integrate HIV programs into primary care; improve supply chain capacity; and address health worker shortages.

  • Open Access
    Barriers to Health Care in Rural Mozambique: A Rapid Ethnographic Assessment of Planned Mobile Health Clinics for ART
    Amee Schwitters, Philip Lederer, Leah Zilversmit, Paula Samo Gudo, Isaias Ramiro, Luisa Cumba, Epifanio Mahagaja and Kebba Jobarteh
    Global Health: Science and Practice March 2015, 3(1):109-116; https://doi.org/10.9745/GHSP-D-14-00145

    Mobile health clinics can markedly decrease clients' transportation time and cost to access antiretroviral therapy (ART) and other health services in rural areas, potentially improving use. Close coordination with community leaders and regularly scheduled visits by the mobile clinics are critical.

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