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Global Health: Science and Practice
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Global Health: Science and Practice

Dedicated to what works in global health programs

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HIV/AIDS

  • Open Access
    Infant Circumcision for Sexually Transmitted Infection Risk Reduction Globally
    Brian J. Morris, Stephen Moreton, John N. Krieger and Jeffrey D. Klausner
    Global Health: Science and Practice August 2022, 10(4):e2100811; https://doi.org/10.9745/GHSP-D-21-00811

    Population-based studies in high-income countries have failed to find that male circumcision protects against sexually transmitted infections. Using evidence from several sources, we show that male circumcision does protect against HIV during insertive intercourse for men who have sex with men.

  • Open Access
    A Cross-Sectional Assessment of HIV Self-Testing Preferences and Uptake Among Key Populations in Phnom Penh, Cambodia
    Michael M. Cassell, Philippe Girault, Sopha Nith, Chandary Rang, Sereyvisith Sokhan, Sovannary Tuot, Vichet Kem, Pagna Dork, Aphyra Chheav, Mary Sos, Chanry Im, Sotheary Meach, Kimrun Mao, Penh Sun Ly, Vohith Khol, Sovannarith Samreth, Bora Ngauv, Vichea Ouk, Sopheap Seng and F. Stephen Wignall
    Global Health: Science and Practice June 2022, 10(3):e2100412; https://doi.org/10.9745/GHSP-D-21-00412

    Offering HIV self-testing services to key populations in Cambodia expanded HIV testing access to a large proportion of individuals with no prior testing history and resulted in high rates of new HIV case detection and subsequent linkages to HIV treatment.

  • Open Access
    “Testing Can Be Done Anywhere”: A Qualitative Assessment of Targeted Community-Based Point-of-Care Early Infant Diagnosis of HIV in Lusaka, Zambia
    Tannia Tembo, Helen Dale, Nobutu Muttau, Megumi Itoh, Dhelia Williamson, Chanda Mwamba, Albert Manasyan, R. Suzanne Beard, Mackenzie Hurlston Cox and Michael E. Herce
    Global Health: Science and Practice June 2022, 10(3):e2100723; https://doi.org/10.9745/GHSP-D-21-00723

    Community-based point-of-care testing is an acceptable, appropriate, and feasible strategy for improving access to HIV diagnostic services for high-risk HIV-exposed infants.

  • Open Access
    “Nothing for Us Without Us”: An Evaluation of Patient Engagement in an HIV Care Improvement Collaborative in the Caribbean
    Shay Bluemer-Miroite, Katy Potter, Elizabeth Blanton, Georgia Simmonds, Conrad Mitchell, Kenyatta Barnaby, Karen Askov Zeribi, Dale Babb, Nicola Skyers, Gabrielle O'Malley and Clive Anderson
    Global Health: Science and Practice June 2022, 10(3):e2100390; https://doi.org/10.9745/GHSP-D-21-00390

    This evaluation suggests that it is both possible and valuable to include patients as partners in quality improvement efforts, especially when resources must be prioritized for the highest impact efforts. Patient engagement in the improvement process is particularly powerful when addressing illnesses that may be stigmatized such as HIV.

  • Open Access
    Leveraging Experience From Active TB Drug-Safety Monitoring and Management for Monitoring Active Antiretroviral Toxicity
    Lisa Stevens, Kelly E. Perry, Iakuna Moide, Francil Kaemala, Justine Nankinga, Anh L. Innes and Ignatius Mogaba
    Global Health: Science and Practice April 2022, 10(2):e2100595; https://doi.org/10.9745/GHSP-D-21-00595

    Systems established for active drug safety monitoring and management of drug-resistant TB should be leveraged to ensure comprehensive surveillance for active toxicity monitoring during scale-up of newer antiretroviral regimens.

  • Open Access
    Uganda Public Health Fellowship Program's Contributions to the National HIV and TB Programs, 2015–2020
    Alex R. Ario, Lilian Bulage, Yvette Wibabara, Peter Muwereza, Daniel Eurien, Steven N. Kabwama, Benon Kwesiga, Daniel Kadobera, Stavia Turyahabwe, Joshua B. Musinguzi, Rhoda K. Wanyenze, Pamela M. Nasirumbi, Deus Lukoye, Julie R. Harris, Lisa A. Mills and Lisa J. Nelson
    Global Health: Science and Practice April 2022, 10(2):e2100574; https://doi.org/10.9745/GHSP-D-21-00574

    The Uganda Public Health Fellowship Program has built the capacity of its fellows to address multiple gaps in the Uganda health system as well as to contribute to improving Uganda's ability to prevent, prepare for, and respond to public health emergencies such as HIV and TB.

  • Open Access
    Sustainability of Funding for HIV Treatment Services: A Cross-Sectional Survey of Patients' Willingness to Pay for Treatment Services in Nigeria
    Olawale Durosinmi-Etti, Bruce Fried, Karine Dubé, Sean Sylvia, Sandra Greene, Akudo Ikpeazu and Emmanuel Kelechi Nwala
    Global Health: Science and Practice April 2022, 10(2):e2100550; https://doi.org/10.9745/GHSP-D-21-00550

    Many Nigerian patients are willing to pay for HIV treatment, but several socioeconomic factors play significant roles in willingness and capacity to pay for treatment and the maximum amounts patients are willing to pay.

  • Open Access
    Casting a Wide Net: HIV Drug Resistance Monitoring in Pre-Exposure Prophylaxis Seroconverters in the Global Evaluation of Microbicide Sensitivity Project
    Lisa Levy, Jill M. Peterson, Lauren D. Kudrick, Bhavna Chohan, Everline Bosek, Irene Mukui, Mary Mugambi, Sarah Masyuko, Owen Mugurungi, Nonhlanhla Ndlovu, Imelda Mahaka, Megan Dunbar, Anita Hettema, Rudo A.P. Kuwengwa, Sindy Matse, Saiqa Mullick, Letitia Greener, Cara O'Connor, Diantha Pillay, Maria Fawzy, John W. Mellors, Urvi M. Parikh and the Global Evaluation of Microbicide Sensitivity (GEMS) project
    Global Health: Science and Practice April 2022, 10(2):e2100122; https://doi.org/10.9745/GHSP-D-21-00122

    Global Evaluation of Microbicide Sensitivity projects in 4 countries demonstrated the feasibility of establishing an HIV drug resistance monitoring program for pre-exposure prophylaxis (PrEP). These projects will provide valuable information on seroconversions in the context of PrEP use and will serve to inform Ministries of Health and policy makers on the need for long-term surveillance approaches.

  • Open Access
    Human-Centered Design for Public Health Innovation: Codesigning a Multicomponent Intervention to Support Youth Across the HIV Care Continuum in Mozambique
    Trena I. Mukherjee, Allison Zerbe, Joanna Falcao, Shauna Carey, Alexandra Iaccarino, Brynn Kolada, Bruno Olmedo, Cady Shadwick, Hitesh Singhal, Lauren Weinstein, Mirriah Vitale, Eduarda De Pimentel De Gusmao and Elaine J. Abrams
    Global Health: Science and Practice April 2022, 10(2):e2100664; https://doi.org/10.9745/GHSP-D-21-00664

    Using a human-centered design approach, we codesigned CombinADO, an intervention to improve antiretroviral therapy adherence and retention in care among adolescents and young people living with HIV (AYAHIV) in Nampula, Mozambique. CombinADO aims to foster peer connectedness and belonging, provide accessible medical knowledge, demystify and destigmatize HIV, and cultivate a sense of hope among AYAHIV.

  • Open Access
    HIV Care Continuum Services for People Who Inject Drugs in Kazakhstan During COVID-19: A Qualitative Study of Service Provider Perspectives
    Tara McCrimmon, Anne Sundelson, Meruyert Darisheva, Louisa Gilbert, Timothy Hunt, Assel Terlikbayeva, Sholpan Primbetova and Nabila El-Bassel
    Global Health: Science and Practice April 2022, 10(2):e2100619; https://doi.org/10.9745/GHSP-D-21-00619

    Needle and syringe programs (NSPs) in Kazakhstan have been crucial in providing care for people who inject drugs (PWID) during the COVID-19 pandemic. Additional supports and investments are needed to ensure that NSPs can continue to reach these marginalized populations while traditional medical systems are under strain.

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