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Global Health: Science and Practice
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Global Health: Science and Practice

Dedicated to what works in global health programs

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HIV/AIDS

  • Open Access
    Leveraging Experience From Active TB Drug-Safety Monitoring and Management for Monitoring Active Antiretroviral Toxicity
    Lisa Stevens, Kelly E. Perry, Iakuna Moide, Francil Kaemala, Justine Nankinga, Anh L. Innes and Ignatius Mogaba
    Global Health: Science and Practice April 2022, 10(2):e2100595; https://doi.org/10.9745/GHSP-D-21-00595

    Systems established for active drug safety monitoring and management of drug-resistant TB should be leveraged to ensure comprehensive surveillance for active toxicity monitoring during scale-up of newer antiretroviral regimens.

  • Open Access
    Implementation of HIV Retesting During Pregnancy and Postpartum in Kenya: A Cross-Sectional Study
    Monalisa Penumetsa, Jillian Neary, Shiza Farid, Peninah Kithao, Barbra A. Richardson, Daniel Matemo, Grace John-Stewart, John Kinuthia and Alison L. Drake
    Global Health: Science and Practice February 2022, 10(1):e2100451; https://doi.org/10.9745/GHSP-D-21-00451

    Strategies are needed to prevent missed opportunities to detect women with incident HIV infection during pregnancy or postpartum and maximize prevention of mother-to-child HIV transmission efforts.

  • Open Access
    Uptake and Short-Term Retention in HIV Treatment Among Men in South Africa: The Coach Mpilo Pilot Project
    Mbuzeleni Hlongwa, Morna Cornell, Shawn Malone, Paris Pitsillides, Kristen Little and Nina Hasen
    Global Health: Science and Practice February 2022, 10(1):e2100498; https://doi.org/10.9745/GHSP-D-21-00498

    In this pilot project, providing peer support to men living with HIV retained a high proportion of men living with HIV in the early stages of HIV treatment and successfully supported men in returning to care after a treatment interruption.

  • Open Access
    How Home Delivery of Antiretroviral Drugs Ensured Uninterrupted HIV Treatment During COVID-19: Experiences From Indonesia, Laos, Nepal, and Nigeria
    Theresa Hoke, Moses Bateganya, Otoyo Toyo, Caroline Francis, Bhagawan Shrestha, Phayvieng Philakone, Satish Raj Pandey, Navindra Persaud, Michael M. Cassell, Rose Wilcher and Hally Mahler
    Global Health: Science and Practice December 2021, 9(4):978-989; https://doi.org/10.9745/GHSP-D-21-00168

    During the COVID-19 pandemic, home delivery of antiretrovirals for HIV treatment proved to be a feasible approach for ensuring treatment continuation amid facility closures and travel restrictions. Antiretroviral home delivery is a model warranting further consideration as an additional option for decentralized drug delivery for HIV treatment.

  • Open Access
    A Quality Improvement Intervention to Inform Scale-Up of Integrated HIV-TB Services: Lessons Learned From KwaZulu-Natal, South Africa
    Santhanalakshmi Gengiah, Kogieleum Naidoo, Regina Mlobeli, Maureen F. Tshabalala, Andrew J. Nunn, Nesri Padayatchi, Nonhlanhla Yende-Zuma, Myra Taylor, Pierre M. Barker and Marian Loveday
    Global Health: Science and Practice September 2021, 9(3):444-458; https://doi.org/10.9745/GHSP-D-21-00157

    Despite being standard of care, gaps in HIV-TB service delivery are present. Quality Improvement methods are effective in uncovering health systems weaknesses that impede efficient delivery of integrated HIV-TB services.

  • Open Access
    A Mixed-Methods Process Evaluation: Integrating Depression Treatment Into HIV Care in Malawi
    Melissa A. Stockton, Caroline E. Minnick, Kazione Kulisewa, Steven M. Mphonda, Mina C. Hosseinipour, Bradley N. Gaynes, Joanna Maselko, Audrey E. Pettifor, Vivian Go, Michael Udedi and Brian W. Pence
    Global Health: Science and Practice September 2021, 9(3):611-625; https://doi.org/10.9745/GHSP-D-20-00607

    Effectively integrating depression treatment into HIV care in low-resource settings will require substantially investing in program supervision, building and maintaining the capacity of providers, integrating into existing electronic medical records systems, and ensuring the availability of psychotherapy counselors.

  • Open Access
    Differentiated Service Delivery Models for HIV Treatment in Malawi, South Africa, and Zambia: A Landscape Analysis
    Amy Huber, Sophie Pascoe, Brooke Nichols, Lawrence Long, Salome Kuchukhidze, Bevis Phiri, Timothy Tchereni and Sydney Rosen
    Global Health: Science and Practice June 2021, 9(2):296-307; https://doi.org/10.9745/GHSP-D-20-00532

    Observing the diversity of differentiated service delivery models for HIV treatment in use in sub-Saharan Africa can help policy makers and program planners to improve decision making for treatment delivery in the future. This effort can inform decisions about how to optimize the distribution of models across facilities and regions and how to plan for budget and resource allocation.

  • Open Access
    Improving Services for HIV-Exposed Infants in Zambia and Cameroon Using a Quality Improvement Collaborative Approach
    Gillian Dougherty, Tihnje Abena, Jean Pierre Abesselo, Jeane Ngala Banda, Tjek Paul Biyaga, Rodrigo Boccanera, Mary Adetinuke Boyd, Mesmey Ebogo, Leoda Hamomba, Suzanne Jed, Zeh Florence Kakanou, Prisca Kasonde, Siphiwe Chilungu Kasonka, Rachael Lungwebungu, Caitlin Madevu-Matson, Magdalene Mange Mayer, Mukuka Mwamba, Milembe Panya, Paul Sakanda, Fatima Tsiouris, Lauren Walker and Miriam Rabkin
    Global Health: Science and Practice June 2021, 9(2):399-411; https://doi.org/10.9745/GHSP-D-20-00550

    To bridge the gap between what is known and what is done, quality improvement collaboratives (QICs) enable health programs to rapidly address quality challenges at scale. Two QICs in Cameroon and Zambia improved coverage of early infant HIV testing and initiating antiretroviral therapy in HIV-exposed infants. The QIC approach empowers health care workers to design solutions tailored for their specific settings.

  • Open Access
    Pathways to Care for Patients With Type 2 Diabetes and HIV/AIDS Comorbidities in Soweto, South Africa: An Ethnographic Study
    Edna N. Bosire, Shane A. Norris, Jane Goudge and Emily Mendenhall
    Global Health: Science and Practice March 2021, 9(1):15-30; https://doi.org/10.9745/GHSP-D-20-00104

    Patients with type 2 diabetes are referred to tertiary hospitals in Soweto although their care could be managed at primary health care clinics. Primary health care needs to be strengthened by addressing health systemic challenges to provide integrated care for comorbid type 2 diabetes and HIV/AIDS.

  • Open Access
    Inpatient Point-of-Care HIV Early Infant Diagnosis in Mozambique to Improve Case Identification and Linkage to Antiretroviral Therapy
    Mércia Matsinhe, Timothy Bollinger, Nilza Lee, Osvaldo Loquiha, Bindiya Meggi, Nédio Mabunda, Chishamiso Mudenyanga, Dadirayi Mutsaka, Marcelina Florêncio, Aurora Mucaringua, Eugénia Macassa, Amir Seni, Ilesh Jani and W. Chris Buck
    Global Health: Science and Practice March 2021, 9(1):31-39; https://doi.org/10.9745/GHSP-D-20-00611

    Introduction of point-of-care early infant diagnosis on the inpatient wards of 2 of the largest pediatric referral hospitals in Mozambique increased HIV testing volume and pediatric HIV case identification with improved linkage to antiretroviral therapy.

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US AIDJohns Hopkins Center for Communication ProgramsUniversity of Alberta

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