High prevalence of the CYP2B6 516G→T(*6) variant and effect on the population pharmacokinetics of efavirenz in HIV/AIDS outpatients in Zimbabwe
…, D Röshammar, E Chigutsa, P Chonzi… - European journal of …, 2008 - Springer
Objective The study sought to investigate the relationship between efavirenz exposure and
the CYP2B6 516G→T(*6) genotype in HIV/AIDS outpatients, using pharmacokinetic …
the CYP2B6 516G→T(*6) genotype in HIV/AIDS outpatients, using pharmacokinetic …
[HTML][HTML] Prevalence of pregnancy induced hypertension and pregnancy outcomes among women seeking maternity services in Harare, Zimbabwe
…, GT Notion, D Bangure, P Chonzi - BMC cardiovascular …, 2015 - Springer
Background Pregnancy induced hypertension (PIH) is one of the most common causes of
both maternal and neonatal morbidity, affecting about 5 – 8 % of pregnant women. It is …
both maternal and neonatal morbidity, affecting about 5 – 8 % of pregnant women. It is …
[HTML][HTML] Enhanced adherence counselling and viral load suppression in HIV seropositive patients with an initial high viral load in Harare, Zimbabwe: operational …
…, S Satyanarayana, KC Takarinda, H Bara, P Chonzi… - PloS one, 2019 - journals.plos.org
Background In people living with HIV (PLHIV) who are on anti-retroviral therapy (ART), it is
essential to identify persons with high blood viral loads (VLs) (≥1000 copies/ml), provide …
essential to identify persons with high blood viral loads (VLs) (≥1000 copies/ml), provide …
[HTML][HTML] CYP2B6*6, CYP2B6*18, Body weight and sex are predictors of efavirenz pharmacokinetics and treatment response: population pharmacokinetic modeling in …
…, B Ngara, C Nhachi, G Kadzirange, P Chonzi… - BMC Pharmacology and …, 2015 - Springer
Background Efavirenz (EFV) therapeutic response and toxicity are associated with high inter-individual
variability attributed to variation in its pharmacokinetics. Plasma concentrations …
variability attributed to variation in its pharmacokinetics. Plasma concentrations …
[HTML][HTML] Virological failure among adolescents on ART, Harare City, 2017-a case-control study
Z Sithole, E Mbizvo, P Chonzi, M Mungati… - BMC infectious …, 2018 - Springer
Background Zimbabwe is on track towards achieving viral suppression among adults (87%).
However, adolescents have only achieved 44% by 2016. In Harare city, 57% of adolescents …
However, adolescents have only achieved 44% by 2016. In Harare city, 57% of adolescents …
The role of community health workers in improving HIV treatment outcomes in children: lessons learned from the ZENITH trial in Zimbabwe
…, G Mchugh, S Munyati, P Chonzi… - Health policy and …, 2018 - academic.oup.com
Reliance on community health workers (CHWs) for HIV care continues to increase,
particularly in resource-limited settings. CHWs can improve HIV service use and adherence to …
particularly in resource-limited settings. CHWs can improve HIV service use and adherence to …
[HTML][HTML] Economic incentives for HIV testing by adolescents in Zimbabwe: a randomised controlled trial
…, E Dauya, G McHugh, S Munyati, P Chonzi… - The lancet HIV, 2018 - thelancet.com
Background HIV testing is the important entry point for HIV care and prevention service, but
uptake of HIV testing and thus coverage of antiretroviral therapy are much lower in older …
uptake of HIV testing and thus coverage of antiretroviral therapy are much lower in older …
[HTML][HTML] Psychological distress among healthcare workers accessing occupational health services during the COVID-19 pandemic in Zimbabwe
…, C Pasi, M Chiwanga, P Chonzi… - Comprehensive …, 2022 - Elsevier
Background Healthcare workers (HCWs) have experienced anxiety and psychological distress
during the COVID-19 pandemic. We established and report findings from an occupational …
during the COVID-19 pandemic. We established and report findings from an occupational …
[HTML][HTML] Community SARS-CoV-2 seroprevalence before and after the second wave of SARS-CoV-2 infection in Harare, Zimbabwe
…, R Rubio-Acero, I Paunovic, A Wieser, P Chonzi… - …, 2021 - thelancet.com
Abstracts Background By the end of July 2021 Zimbabwe, has reported over 100,000 SARS-CoV-2
infections. The true number of SARS-CoV-2 infections is likely to be much higher. We …
infections. The true number of SARS-CoV-2 infections is likely to be much higher. We …
[HTML][HTML] The effect of community-based support for caregivers on the risk of virological failure in children and adolescents with HIV in Harare, Zimbabwe (ZENITH): an …
…, G Mchugh, H Mujuru, P Chonzi… - The Lancet Child & …, 2017 - thelancet.com
Background Children and adolescents have poorer HIV treatment outcomes than adults.
We aimed to assess the effect of community-based support for caregivers of HIV-infected …
We aimed to assess the effect of community-based support for caregivers of HIV-infected …