Tourette's syndrome (TS) is a genetically influenced developmental neuropsychiatric disorder
characterized by chronic vocal and motor tics. We studied Slit and Trk-like 1 (SLITRK1) as …

To further define the role of a T-box transcription factor, Tbx5, in cardiac development, we
have examined its expression in the developing mouse and chick heart and correlated this …

Background The accuracy of microbial community surveys based on marker-gene and
metagenomic sequencing (MGS) suffers from the presence of contaminants—DNA sequences …

Substituted pyrroles were prepared by a gold(I)-catalyzed acetylenic Schmidt reaction of
homopropargyl azides. The reaction allows for regiospecific substitution at each position of the …

Cyclin-dependent kinases (CDK) are key positive regulators of cell cycle progression and
attractive targets in oncology. SCH 727965 inhibits CDK2, CDK5, CDK1, and CDK9 activity in …

The serine/threonine kinase glycogen synthase kinase-3 (GSK-3) was initially identified and
studied in the regulation of glycogen synthesis. GSK-3 functions in a wide range of cellular …

The EGFR/PI3K/PTEN/Akt/mTORC1/GSK-3 pathway plays prominent roles in malignant
transformation, prevention of apoptosis, drug resistance and metastasis. The expression of this …

Glycogen synthase kinase-3 (GSK-3) is well documented to participate in a complex array
of critical cellular processes. It was initially identified in rat skeletal muscle as a serine/…

Rapid vehicle growth in developing nations makes it necessary for these nations to address
the transportation and environmental impacts of on-road mobile sources. To estimate the air …

An increasing number of travel, tourism, and hospitality management programs are developing
and implementing online courses. Faculty and students are encountering advantages …