Saving mothers, giving life: it takes a system to save a mother (Republication)

…, L Marum, J Healey, J LaBrecque… - … Health: Science and …, 2019 - ghspjournal.org
Background: Ending preventable maternal and newborn deaths remains a global health
imperative under United Nations Sustainable Development Goal targets 3.1 and 3.2. Saving …

[HTML][HTML] Addressing the third delay in Saving Mothers, Giving Life districts in Uganda and Zambia: ensuring adequate and appropriate facility-based maternal and …

…, F Luwaga, MM Schmitz, J LaBrecque… - … Health: Science and …, 2019 - ghspjournal.org
Background: Saving Mothers, Giving Life (SMGL) is a 5-year initiative implemented in participating
districts in Uganda and Zambia that aimed to reduce deaths related to pregnancy and …

Utilization of the repeated squat-stand model for studying the directional sensitivity of the cerebral pressure-flow relationship

L Labrecque, JD Smirl… - Journal of Applied …, 2021 - journals.physiology.org
Hysteresis in the cerebral pressure-flow relationship describes the superior ability of the
cerebrovasculature to buffer cerebral blood flow changes when mean arterial pressure (MAP) …

Point/counterpoint: we should take the direction of blood pressure change into consideration for dynamic cerebral autoregulation quantification

L Labrecque, JD Smirl, YC Tzeng… - Journal of Cerebral …, 2022 - journals.sagepub.com
Accumulating evidence suggests asymmetrical responses of cerebral blood flow during
large transient changes in mean arterial pressure. Specifically, the augmentation in cerebral …

Reproducibility and diurnal variation of the directional sensitivity of the cerebral pressure-flow relationship in men and women

L Labrecque, JS Burma, MA Roy… - Journal of Applied …, 2022 - journals.physiology.org
The cerebral pressure-flow relationship has directional sensitivity, meaning the augmentation
in cerebral blood flow is attenuated when mean arterial pressure (MAP) increases versus …

Losing the dogmatic view of cerebral autoregulation

P Brassard, L Labrecque, JD Smirl… - Physiological …, 2021 - Wiley Online Library
In 1959, Niels Lassen illustrated the cerebral autoregulation curve in the classic review article
entitled Cerebral Blood Flow and Oxygen Consumption in Man. This concept suggested a …

Dynamic cerebral autoregulation is attenuated in young fit women

L Labrecque, K Rahimaly, S Imhoff… - Physiological …, 2019 - Wiley Online Library
Young women exhibit higher prevalence of orthostatic hypotension with presyncopal symptoms
compared to men. These symptoms could be influenced by an attenuated ability of the …

Quantification of dynamic cerebral autoregulation: welcome to the jungle!

P Brassard, MA Roy, JS Burma, L Labrecque… - Clinical Autonomic …, 2023 - Springer
Purpose Patients with dysautonomia often experience symptoms such as dizziness,
syncope, blurred vision and brain fog. Dynamic cerebral autoregulation, or the ability of the …

Diminished dynamic cerebral autoregulatory capacity with forced oscillations in mean arterial pressure with elevated cardiorespiratory fitness

L Labrecque, K Rahimaly, S Imhoff… - Physiological …, 2017 - Wiley Online Library
The effect that cardiorespiratory fitness has on the dynamic cerebral autoregulatory capacity
during changes in mean arterial pressure ( MAP ) remains equivocal. Using a multiple‐…

[HTML][HTML] On the need of considering cardiorespiratory fitness when examining the influence of sex on dynamic cerebral autoregulation

L Labrecque, JD Smirl… - American Journal of …, 2019 - journals.physiology.org
TO THE EDITOR: We read with great interest the recent article by Favre and Serrador (2).
We would like to commend these authors on their thorough study, which reported dynamic …