[HTML][HTML] Variation and risk factors of drug resistant tuberculosis in sub-Saharan Africa: a systematic review and meta-analysis
D Lukoye, W Ssengooba, K Musisi, GW Kasule… - BMC public health, 2015 - Springer
Background Prevalence of multidrug resistant tuberculosis (MDR-TB), defined as in vitro
resistance to both rifampicin and isoniazid with or without resistance to other TB drugs, in sub-…
resistance to both rifampicin and isoniazid with or without resistance to other TB drugs, in sub-…
[HTML][HTML] Anti-tuberculosis drug resistance among new and previously treated sputum smear-positive tuberculosis patients in Uganda: results of the first national survey
D Lukoye, F Adatu, K Musisi, GW Kasule, W Were… - PloS one, 2013 - journals.plos.org
Background Multidrug resistant and extensively drug resistant tuberculosis (TB) have become
major threats to control of tuberculosis globally. The rates of anti-TB drug resistance in …
major threats to control of tuberculosis globally. The rates of anti-TB drug resistance in …
[HTML][HTML] Prevalence and patterns of rifampicin and isoniazid resistance conferring mutations in Mycobacterium tuberculosis isolates from Uganda
E Kigozi, GW Kasule, K Musisi, D Lukoye, S Kyobe… - PLoS …, 2018 - journals.plos.org
Background Accurate diagnosis of tuberculosis, especially by using rapid molecular assays,
can reduce transmission of drug resistant tuberculosis in communities. However, the …
can reduce transmission of drug resistant tuberculosis in communities. However, the …
[HTML][HTML] Whole genome sequencing to complement tuberculosis drug resistance surveys in Uganda
W Ssengooba, CJ Meehan, D Lukoye… - Infection, Genetics and …, 2016 - Elsevier
Understanding the circulating Mycobacterium tuberculosis resistance mutations is vital for
better TB control strategies, especially to inform a new MDR-TB treatment programme. We …
better TB control strategies, especially to inform a new MDR-TB treatment programme. We …
[HTML][HTML] Addressing the drug-resistant tuberculosis challenge through implementing a mixed model of care in Uganda
…, H Luwaga, E Kizito, S Turyahabwe, D Lukoye… - PloS one, 2020 - journals.plos.org
Worldwide, Drug-resistant Tuberculosis (DR-TB) remains a big problem; the diagnostic
capacity has superseded the clinical management capacity thereby causing ethical challenges. …
capacity has superseded the clinical management capacity thereby causing ethical challenges. …
[HTML][HTML] Rates of anti-tuberculosis drug resistance in Kampala-Uganda are low and not associated with HIV infection
D Lukoye, FGJ Cobelens, N Ezati, S Kirimunda… - PloS one, 2011 - journals.plos.org
Background Drug resistance among tuberculosis patients in sub-Saharan Africa is increasing,
possibly due to association with HIV infection. We studied drug resistance and HIV …
possibly due to association with HIV infection. We studied drug resistance and HIV …
[HTML][HTML] Epidemiology of tuberculosis in children in Kampala district, Uganda, 2009–2010; a retrospective cross-sectional study
E Wobudeya, D Lukoye, IR Lubega, F Mugabe… - BMC public health, 2015 - Springer
Background The global tuberculosis (TB) estimate in 2011 was 500,000 cases among children
under 15 years representing 5.7 % of all cases and 64, 000 deaths among HIV negative …
under 15 years representing 5.7 % of all cases and 64, 000 deaths among HIV negative …
[HTML][HTML] Frequency and patterns of second-line resistance conferring mutations among MDR-TB isolates resistant to a second-line drug from eSwatini, Somalia and …
…, E Kigozi, FA Katabazi, D Lukoye… - BMC pulmonary …, 2019 - Springer
Background Pulmonary tuberculosis is a leading cause of morbidity and mortality in developing
countries. Drug resistance, a huge problem in this contagious disease, is driven by point …
countries. Drug resistance, a huge problem in this contagious disease, is driven by point …
[HTML][HTML] Trend and outcome of notified children with tuberculosis during 2011-2015 in Kampala, Uganda
…, M Sekadde-Kasirye, D Kimuli, F Mugabe, D Lukoye - BMC public health, 2017 - Springer
Background The road map for childhood tuberculosis launched in 2013 provided strong
renewed efforts focused towards zero deaths due to tuberculosis in children. From 2010, there …
renewed efforts focused towards zero deaths due to tuberculosis in children. From 2010, there …
The T2 Mycobacterium tuberculosis genotype, predominant in Kampala, Uganda, shows negative correlation with antituberculosis drug resistance
D Lukoye, FA Katabazi, K Musisi… - Antimicrobial agents …, 2014 - Am Soc Microbiol
Surveillance of the circulating Mycobacterium tuberculosis complex (MTC) strains in a given
locality is important for understanding tuberculosis (TB) epidemiology. We performed …
locality is important for understanding tuberculosis (TB) epidemiology. We performed …