During 2015-2018, seven schools in rural Vietnam experienced diphtheria outbreaks. Multilocus sequence types were the same within schools but differed between schools. Low vaccine coverage and crowded dormitories might have contributed to the outbreaks. Authorities should consider administering routine vaccinations and booster doses for students entering the school system.
Keywords: Corynebacterium diphtheriae; Vietnam; bacteria; central highland districts; diphtheria; epidemic; epidemiology; multilocus sequence typing; outbreaks; schools.