Solar-Powered Oxygen Delivery in Low-Resource Settings: A Randomized Clinical Noninferiority Trial

Michael T Hawkes; Andrea L Conroy; Sophie Namasopo; Ravi Bhargava; Kevin C Kain; Qaasim Mian; Robert O Opoka

doi:10.1001/jamapediatrics.2018.0228

Solar-Powered Oxygen Delivery in Low-Resource Settings: A Randomized Clinical Noninferiority Trial

JAMA Pediatr. 2018 Jul 1;172(7):694-696. doi: 10.1001/jamapediatrics.2018.0228.

Authors

Michael T Hawkes^{1

2}, Andrea L Conroy³, Sophie Namasopo⁴, Ravi Bhargava⁵, Kevin C Kain^{6

7}, Qaasim Mian⁸, Robert O Opoka⁹

Affiliations

¹ Department of Pediatrics, School of Public Health, University of Alberta, Edmonton Clinic Health Academy, Edmonton, Alberta, Canada.
² Department of Medical Microbiology & Immunology, School of Public Health, University of Alberta, Edmonton Clinic Health Academy, Edmonton, Alberta, Canada.
³ Ryan White Center for Pediatric Infectious Diseases and Global Health, Indiana University School of Medicine, Indianapolis.
⁴ Department of Paediatrics, Jinja Regional Referral Hospital, Jinja, Uganda.
⁵ Department of Diagnostic Imaging, University of Alberta, WC Mackenzie Health Sciences Centre, Edmonton, Alberta, Canada.
⁶ Sandra A. Rotman Laboratories, Sandra Rotman Centre for Global Health, University Health Network-Toronto General Hospital, Medical and Related Sciences Centre, Toronto, Ontario, Canada.
⁷ Department of Medicine, University of Toronto, Tropical Disease Unit, University Health Network-Toronto General Hospital, Medical and Related Sciences Centre, Toronto, Ontario, Canada.
⁸ Faculty of Medicine, University of Alberta, Edmonton Clinic Health Academy, Edmonton, Alberta, Canada.
⁹ Department of Paediatrics and Child Health, Mulago Hospital and Makerere University, Kawempe, Kampala, Uganda.

Abstract

This randomized clinical noninferiority trial compares solar-powered oxygen delivery vs standard oxygen delivery using compressed oxygen cylinders among children younger than 13 years with hypoxemic illness at 2 resource-constrained hospitals in Uganda.

Trial registration: ClinicalTrials.gov NCT02100865.

Publication types

Multicenter Study
Randomized Controlled Trial
Research Support, Non-U.S. Gov't

MeSH terms

Child, Preschool
Developing Countries
Equivalence Trials as Topic
Female
Humans
Hypoxia / mortality
Hypoxia / therapy*
Infant
Infant, Newborn
Length of Stay / statistics & numerical data
Male
Medically Underserved Area*
Oxygen Inhalation Therapy / instrumentation*
Oxygen Inhalation Therapy / methods
Solar Energy*
Time Factors
Treatment Outcome
Uganda / epidemiology

Associated data

ClinicalTrials.gov/NCT02100865