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Home / The International Journal of Tuberculosis and Lung Disease, Volume 19, Number 3

The impact of Xpert® MTB/RIF depends on service coordination: experience in Burkina Faso

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Translating the potential of Xpert® MTB/RIF into more effective tuberculosis (TB) care and control in low-income settings is challenged by operational issues. We report the experience in introducing this technology in Burkina Faso through a centralised approach. Xpert was successfully integrated into the diagnostic algorithm of multidrug-resistant TB cases. However, barriers to Xpert use for the diagnosis of TB in vulnerable populations, such as persons living with human immunodeficiency virus infection and children, were observed, mainly due to lack of coordination between services. Lessons learnt can be exploited to optimise the roll-out of this technology at country level.

Keywords: MDR-TB; PLHIV; childhood TB; prisoners; resource-constrained countries

Document Type: Research Article

Affiliations: 1: *National Tuberculosis Program, Ministry of Health, Ouagadougou, Burkina Faso 2: †University Division of Infectious and Tropical Disease, World Health Organization (WHO) Collaborating Centre for TB/HIV Activities and for TB Elimination, University of Brescia, Brescia 3: ‡Emerging Pathogens Unit, TB Supranational Reference laboratory, San Raffaele Scientific Institute, Milan, Italy 4: §Global TB Programme, TB/HIV and Community Engagement Unit, WHO, Geneva, Switzerland

Publication date: 01 March 2015

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  • The International Journal of Tuberculosis and Lung Disease (IJTLD) is for clinical research and epidemiological studies on lung health, including articles on TB, TB-HIV and respiratory diseases such as COVID-19, asthma, COPD, child lung health and the hazards of tobacco and air pollution. Individuals and institutes can subscribe to the IJTLD online or in print – simply email us at [email protected] for details.

    The IJTLD is dedicated to understanding lung disease and to the dissemination of knowledge leading to better lung health. To allow us to share scientific research as rapidly as possible, the IJTLD is fast-tracking the publication of certain articles as preprints prior to their publication. Read fast-track articles.

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