Outcome Variables of a Special Neonatal Care Unit Point-of-Care Quality Improvement Intervention, Madhya Pradesh, India
| Preintervention Period, No./Total (%) | Intervention Period, No./Total (%) | AdjustedaOdds Ratio or Mean Difference (95% CI) | |
|---|---|---|---|
| Death before discharge | 343/3352 (10.2) | 1106/10469 (10.6) | 0.93 (0.80, 1.09) |
| Adverse outcomeb | 519/3352 (15.5) | 1761/10469 (16.8) | 1.01 (0.90, 1.15) |
| Oxygen started at admission | 1608/3352 (48.0) | 3778/10469 (36.1) | 0.60 (0.55, 0.66) |
| CPAP started at admission | 69/3352 (2.1) | 186/10469 (1.8) | 0.80 (0.58, 1.10) |
| Temperature at admission | 2958/3352 (88.2) | 9648/10469 (92.2) | 1.54 (1.33, 1.79) |
| Enteral feeds started within 24 hours of admission | 1254/3217 (39.0) | 4250/10360 (41.0) | 1.17 (1.07, 1.29) |
| Breast milk as first feed | 922/3352 (27.5) | 2961/10469 (28.3) | 1.10 (0.99, 1.22) |
| Use of dairy milk for feeding | 1655/3352 (49.4) | 3535/10469 (33.8) | 0.34 (0.31, 0.38)c |
| Use of phototherapy | 684/3115 (22.0) | 1838/10095 (18.2) | 0.82 (0.74, 0.92) |
| Peak serum bilirubin >20 mg/dL | 14/3352 (1.9) | 36/10469 (1.8) | 1.02 (0.50, 2.10) |
| Use of any systemic antibiotic | 845/2166 (39.0) | 2982/10315 (29.4) | 0.76 (0.68, 0.85) |
| Reach full enteral feeds, No. (95% CI), days | 8.0 (5.0, 12.0) | 6.0 (3.0, 11.0) | −2.2 (−4.00, −0.40) |
| Oxygen therapy, No. (95% CI), days | 2.0 (1.0, 2.0) | 1.0 (1.0, 2.0) | −0.3 (−0.50, −0.20) |
| ROP screeningd | 320/2052 (15.6) | 483/6410 (7.5) | 0.44 (0.37, 0.52) |
Abbreviations: CI, confidence interval; CPAP, continuous positive airway pressure; ROP, retinopathy of prematurity.
↵aAdjusted for center, gestation at birth, gender, presence of congenital malformation, antenatal care, outborn status, and need of positive pressure ventilation at birth.
↵bDeath, left against medical advice, or referred.
↵cSimple logistic regression as mixed effects model did not fit.
↵dAmong neonates with birth gestation less than 37 weeks or weight less than 2000 g.