Association Between EVD Comprehensive Knowledge and Uptake of Prevention Practices, Adjusted for Sociodemographic Characteristics in 6 Districts in Uganda, 2020
| Total N=1,629a | Prevention Practicesb % (95% CI) | Adjusted Model for Prevention Practicesc | ||
|---|---|---|---|---|
| aPR (95% CI) | P Value | |||
| Comprehensive knowledge | ||||
| No | 805 | 4.0 (2.2, 8.4) | Reference | |
| Yes | 824 | 4.8 (2.2, 10.3) | 1.87 (1.08, 3.25) | .026d |
| District category | ||||
| Low-risk | 260 | 2.5 (0.9, 6.5) | Reference | |
| High-risk | 1,369 | 4.7 (2.4, 8.9) | 1.25 (0.55, 2.83) | .59d |
| Sex | ||||
| Female | 971 | 3.8 (2.0, 7.0) | Reference | |
| Male | 658 | 6.2 (2.6, 14.0 | 1.50 (0.84, 2.67) | .17d |
| Age, yearse | ||||
| 15–24 | 365 | 5.1 (2.0, 12.4) | Reference | |
| 25–34 | 424 | 4.4 (1.8, 10.2) | 1.28 (0.68, 2.42) | .45 |
| 35–44 | 346 | 6.7 (3.0, 14.1) | 1.17 (0.57, 2.40) | .67 |
| 45–59 | 319 | 3.0 (1.1, 8.4) | 0.62 (0.25, 1.51) | .29 |
| 60 and older | 175 | 2.2 (0.3, 13.7) | 0.31 (0.08, 1.23) | .10 |
| Educational level | ||||
| No formal education | 276 | 11.8 (5.1, 25.1) | 1.49 (0.67, 3.33) | .33 |
| Primary | 797 | 3.1 (1.2, 7.3) | 0.67 (0.42, 1.09) | .11 |
| Secondary or higher | 556 | 4.2 (1.5, 11.0) | Reference | |
| Religion | ||||
| Christian | 1,451 | 4.5 (2.4, 8.2) | Reference | |
| Muslim | 140 | 5.9 (1.8, 17.7) | 0.97 (0.39, 2.41) | .95 |
| Other | 38 | 0.5 (0.1, 3.5) | 0.71 (0.13, 3.79) | .69 |
Abbreviations: aPR, adjusted Prevalence Ratio estimated using Generalized Estimating Equation (GEE) modified Poisson model; CI, confidence interval; EVD, Ebola virus disease.
↵a Analysis was performed for respondents who reported to ever heard of EVD and took action to avoid getting EVD (n=1,718) and had complete cases (N=1,629) on all factors listed in the table. 89/1,718 (5%) respondents had missing data: on comprehensive knowledge variable (n=87), educational level (n=2), religion (n=1).
↵b Percent of total respondents in a specific category (row percentage).
↵c Estimates from multivariable GEE modified Poisson model including priori selected factors as presented in the table. There was no evidence of multicollinearity among predictors included in multivariable model; variance inflation factor for all factors included in multivariable model was <3. In separate models for “Knowledge of all 3 key knowledge measures”: (aPR:2.16, 95% CI=1.08, 4.32; P=.029), and “Rejected all 3 key EVD misconceptions”: aPR:1.39 (95% CI=0.68, 2.85; P=.361).
↵d Adjusted model results after completing missing values using multiple imputation using chained equations (MICE): N=3,485, comprehensive knowledge (aPR: 1.84, 95% CI=1.06, 3.21; P=.031), District type (high risk versus low risk: aPR: 1.04, 95%CI=0.44, 2.47; P=.927), gender (male versus female: aPR: 1.52, 95% CI=0.85, 2.72; P=160).
↵e Age categorized as per the 2016 Uganda Demographic and Health Survey.25