Predictors of Loss to Follow-Up at Delivery and 6 and 14 Weeks Postpartum (Complementary Log-Log Regression Model)
| Baseline Model (N=404) | Final Model (N=404) | |||
|---|---|---|---|---|
| HR (95% CI) | P Value | HR (95% CI) | P Value | |
| Time point | ||||
| Delivery | 1 | 1 | ||
| 6 weeks postpartum | 0.21 (0.10, 0.43) | <.001 | 0.27 (0.10, 0.70) | <.001 |
| 14 weeks postpartum | 0.76 (0.49, 1.13) | .18 | 0.47 (0.22, 0.89) | .003 |
| Living arrangements | ||||
| Lives with partner/spouse/children | 1 | |||
| Lives by herself or with other relatives/friends | 0.74 (0.29, 1.65) | .50 | ||
| Employment status | ||||
| Not employed | 1 | 1 | ||
| Employed | 1.69 (1.07, 2.33) | .03 | 1.2 (0.81, 1.13) | .28 |
| Home district | ||||
| Kisumu | 1 | |||
| Other | 1.22 (0.80, 1.73) | .35 | ||
| Pregnancy duration at recruitment | ||||
| 14–28 weeks | 1 | |||
| 29–36 weeks | 1.08 (0.69, 1.58) | .73 | ||
| Total pregnancies, including current | 1.00 (0.90, 1.10) | .95 | ||
| Has had HIV-affected child (living/died) | ||||
| No | 1 | |||
| Yes | 0.89 (0.47, 1.56) | .72 | ||
| Duration of knowing own HIV status | ||||
| <5 years | 1 | 1 | ||
| ≥5 years | 0.62 (0.39, 0.97) | .04 | 0.83 (0.49, 1.06) | .33 |
| Disclosure of HIV status to spouse/partner | ||||
| Not disclosed | 1 | 1 | ||
| Disclosed | 0.68 (0.44, 1.00) | 0.05 | 0.93 (0.58, 1.09) | .68 |
| Awareness of partner's HIV status | ||||
| Does not know | 1 | 1 | ||
| Knows, partner positive | 0.62 (0.38, 0.96) | .03 | 0.81 (0.47, 1.06) | .27 |
| Knows, partner negative | 0.81 (0.45, 1.34) | .46 | 0.99 (0.54, 1.12) | .97 |
| Stigma score (16–64) at baseline | 1.01 (0.98, 1.04) | .57 | ||
| Depression score (10–60) at baseline | 1.02 (1.00, 1.03) | .046 | 1.00 (0.98, 1.00) | .55 |
| General health perception (0–100) at baseline | 0.98 (0.97, 0.99) | <.001 | 0.99 (0.98, 1.00) | .01 |
| Experience of physical/sexual violence from partner at baseline | ||||
| Never | 1 | |||
| At least once | 1.33 (0.90, 1.81) | .15 | ||
| Baseline viral load | ||||
| <1000 | 1 | |||
| ≥1000 | 1.02 (0.40, 1.86) | .96 | ||
| CD4 count at enrollment | ||||
| ≤350 | 1 | |||
| 351–500 | 0.70 (0.34, 1.33) | .30 | ||
| >500 | 0.81 (0.45, 1.36) | .47 | ||
| ART experience | ||||
| Naïve | 1 | |||
| Experienced | 0.80 (0.52, 1.17) | .26 | ||
| Study group assignment | ||||
| Control | 1 | 1 | ||
| Intervention | 0.22 (0.11, 0.46) | <.001 | 0.29 (0.12, 0.69) | <.001 |
| Interaction between time point and study group | ||||
| Delivery | 1 | 1 | ||
| 6 weeks postpartum * Intervention | 1.10 (0.21, 2.33) | .90 | 1.05 (0.22, 1.14) | .93 |
| 14 weeks postpartum * Intervention | 3.35 (2.19, 2.41) | <.001 | 1.86 (2.01, 1.14) | <.001 |
Abbreviations: ART, antiretroviral therapy; CD4, cluster of differentiation 4; CI, confidence interval; HR, hazard ratio.
Note: Both baseline and final models are controlled for age, education, and marital status. All baseline models were tested for interaction effect with the time variable. The time interaction effect is included only if it is significant (P<.05). Final model comprised of variables that were significant in the baseline models.