TABLE 2.

Additional MANDATE Model Assumptions, Sub-Saharan Africa, 2015

AssumptionsValue
Preterm births in sub-Saharan Africa, N3,988,000
Delivery location in sub-Saharan Africa, %
Home50
Clinic35
Hospital15
Antenatal care location in sub-Saharan Africa, %
Home30
Clinic65
Hospital5
Preterm subconditions contributing to preterm mortality, Prevalence | Case fatality rate,a %
Respiratory distress20 | 35
Intraventricular hemorrhage7 | 7.5
Necrotizing enterocolitis1 | 25
Sepsis9 | 40
Birth asphyxia20 | 20
Preterm with no other conditions43 | 2.1
Diagnostics, Baseline penetration | Baseline utilization | Efficacy for Home/Clinic/Hospital, %
Preterm labor515350/85/90 | 5/20/35 | 25/80/80
Respiratory distress syndrome46,5450/85/90 | 40/60/95 | 75/95/95
Intraventricular hemorrhage5450/85/90 | 5/40/70 | 25/45/45
Necrotizing enterocolitis545650/85/90 | 5/40/70 | 25/85/85
Sepsis49,57,5895/85/90 | 75/80/90 | 75/95/95
Low birth weight5950/85/90 | 5/75/90 | 25/95/95
  • Abbreviation: MANDATE, Maternal and Neonatal Directed Assessment of Technology.

  • a The prevalence and case fatality rates assume no preventive or treatment interventions.