Estimated Microcephaly Cases and Microcephaly Background Prevalence Using Established and Proposed Microcephaly Case Definitions in Neonates Born Between August 1, 2014, to March 31, 2016, in Rural Guatemala
| Origin of Case Definition | Microcephaly No. (%) | Microcephaly Background Prevalence per 10,000 Live Births |
|---|---|---|
| Brazil MOH 1 | 125 (42.2)a | 4,223 |
| Brazil MOH 2 | 48 (16.2)a | 1,622 |
| WHO 2 | 43 (14.5)b | 1,453 |
| WHO 1 | 36 (12.2)b | 1,216 |
| PAHO 2 | 20 (6.8)a | 676 |
| Fenton 2 | 20 (6.8)a | 676 |
| PAHO 1 | 15 (5.1)a | 507 |
| Fenton 1 | 13 (4.4)a | 439 |
| WHO 3 | 9 (3.0)b | 304 |
| Fenton 3 | 1 (0.3)a | 34 |
Abbreviations: MOH, Ministry of Health; PAHO, Pan American Health Organization; WHO, World Health Organization.
↵a Based on infant's estimated GA using z-score of zero for length on Fenton growth curve adjusted for gender. Term if estimated GA ≥37 weeks; preterm if estimated GA <37 weeks.
↵b Assumes term (≥37 weeks) GA for all infants.