TY - JOUR T1 - Do Children With Congenital Zika Syndrome Have Cerebral Palsy? JF - Global Health: Science and Practice JO - GLOB HEALTH SCI PRACT DO - 10.9745/GHSP-D-21-00575 VL - 10 IS - 5 SP - e2100575 AU - Alessandra Carvalho AU - Egmar Longo AU - Cristiana Nascimento-Carvalho AU - Nayara Argollo AU - Kátia Edni Coelho AU - Aline Sampaio AU - Carlos Brites AU - Rita Lucena Y1 - 2022/10/31 UR - http://www.ghspjournal.org/content/10/5/e2100575.abstract N2 - Key MessagesChildren with congenital Zika syndrome should consistently be described as having cerebral palsy when meeting the criteria for this diagnosis.Having access to cerebral palsy–based services will help families and health care professionals in their rehabilitation approaches for children with congenital Zika syndrome.Resumo em português no final do artigo.According to the Definition and Classification of Cerebral Palsy, April 2006, cerebral palsy (CP) refers to1:a group of permanent disorders of movement and posture, causing activity limitation, that are attributed to non-progressive disturbances that occurred in the developing fetal or infant brain. In addition to the motor symptoms, disturbances of sensation, perception, cognition, communication, behaviour, epilepsy, and secondary musculoskeletal abnormalities may also be present.Intrauterine infections, including congenital infections, are reported to be the identified etiology in 5%–10% of cases of CP, with congenital cytomegalovirus being the most common viral infection related to this diagnosis.2In 2015, an outbreak of the Zika virus was reported in Brazil, followed by a significant increase in the prevalence of congenital microcephaly and neurological abnormalities in children born to mothers infected with the Zika virus during pregnancy.3 The causal link between those events was confirmed, and vertical transmission of the virus was established for the first time.4,5 The affected children were soon described as having congenital Zika syndrome (CZS). The classic phenotype comprised severe microcephaly and partly collapsed skull, typical neuroimaging features (cerebral atrophy and subcortical calcifications), ocular abnormalities (macular scarring and focal pigmentary retinal mottling), arthrogryposis, and early severe hypertonia.6 This classic clinical picture was reported to be present in 5%–14% of the infected newborns.7 A thorough analysis of the literature showed that the clinical and neuroradiological features could be present in a spectrum of severity, even though the majority of the … ER -