PT - JOURNAL ARTICLE AU - Teachout, Emily AU - Rowe, Laura A. AU - Pachon, Helena AU - Tsang, Becky L. AU - Yeung, Lorraine F. AU - Rosenthal, Jorge AU - Razzaghi, Hilda AU - Moore, Meredith AU - Panagides, Dora AU - Milani, Peiman AU - Cannon, Michael J. TI - Systematic Process Framework for Conducting Implementation Science Research in Food Fortification Programs AID - 10.9745/GHSP-D-20-00707 DP - 2021 Jun 30 TA - Global Health: Science and Practice PG - 412--421 VI - 9 IP - 2 4099 - http://www.ghspjournal.org/content/9/2/412.short 4100 - http://www.ghspjournal.org/content/9/2/412.full SO - GLOB HEALTH SCI PRACT2021 Jun 30; 9 AB - Key MessagesThere are many countries implementing food fortification programs but not all of them are achieving their public health goals.Implementation challenges are best addressed not in an ad hoc way, but rather through a systematic approach known as implementation science.The need for implementation science research in public health nutrition programs has been well-recognized.Implementation research teams (often composed of scientists, program implementers, and funders) should work together through a systematic process of identifying and addressing gaps in the implementation of a food fortification program.This framework provides a systematic way to identify gaps in context-specific programmatic knowledge and action, formulate implementation research questions, prioritize those questions, and supply guidance on how to move forward after the conclusion and analysis of the implementation research studies.Food fortification has proven to be an effective approach for preventing micronutrient deficiencies in many settings. Factors that lead to successful fortification programs are well established. However, due to the multisectoral nature of fortification and the added complexities present in many settings, the barriers to success are not always evident and the strategies to address them are not always obvious. We developed a systematic process for identifying and addressing gaps in the implementation of a food fortification program. The framework is composed of 4 phases: (1) connect program theory of change to program implementation; (2) develop an implementation research agenda; (3) conduct implementation research; and (4) analyze findings and develop/disseminate recommendations for next steps. We detail steps in each phase to help guide teams through the process. To our knowledge, this is the first attempt to outline a systematic process for applying implementation science research to food fortification. The development of this framework is intended to promote implementation research in the field of food fortification, thus improving access to and effectiveness of this key public health intervention.