RT Journal Article SR Electronic T1 Determinants of Facility-Level Use of Electronic Immunization Registries in Tanzania and Zambia: An Observational Analysis JF Global Health: Science and Practice JO GLOB HEALTH SCI PRACT FD Johns Hopkins University- Global Health. Bloomberg School of Public Health, Center for Communication Programs SP 488 OP 504 DO 10.9745/GHSP-D-20-00134 VO 8 IS 3 A1 Carnahan, Emily A1 Ferriss, Ellen A1 Beylerian, Emily A1 Mwansa, Francis Dien A1 Bulula, Ngwegwe A1 Lyimo, Dafrossa A1 Kalbarczyk, Anna A1 Labrique, Alain B. A1 Werner, Laurie A1 Shearer, Jessica C. YR 2020 UL http://www.ghspjournal.org/content/8/3/488.abstract AB Key FindingsWe provide a framework to quantify the facility-level use of electronic immunization registry (EIR) systems.Facility EIR use declined over time in all study regions in Tanzania and Zambia.There was greater EIR utilization among facilities at which health care workers reported into electronic systems only compared to parallel paper and electronic systems.Key ImplicationsAs more countries transition to EIRs, it is important to understand whether and why health care workers at facilities are adopting and using these systems.As EIRs are introduced in new settings, we recommend building indicators of engagement and use directly into the system for routine monitoring and implementing changes as needed. Background:As more countries transition from paper-based to electronic immunization registries (EIRs) to collect and track individual immunization data, guidance is needed for successful adoption and use of these systems. Little research is available on the determinants of EIR use soon after introduction. This observational study assesses the determinants of facility health care workers’ use of new EIRs in Tanzania and Zambia, implemented during 2016 to 2018.Methods:We used EIR data entered between 2016 and 2018 from 3 regions in Tanzania and 1 province in Zambia to measure weekly EIR system use for a total of 50,639 facility-weeks. We joined secondary data on facility characteristics and applied the Performance of Routine Information System Management framework to categorize characteristics as organizational, technical, or behavioral. We used a generalized estimating equations logistic regression model to assess facility characteristics as potential determinants of system use.Results:In both countries, the estimated odds of weekly EIR use declined weekly after EIR introduction. In Tanzania, health centers and hospitals had increased odds of system use compared to dispensaries. For each additional health care worker trained in a facility during the EIR introduction, the estimated odds of weekly EIR use increased. Tanzanian facilities that had transitioned entirely to paperless reporting had higher odds of sustained use compared to those maintaining parallel electronic and paper-based reporting systems. In Zambia, distance from the district health office was significantly associated with decreasing odds of system use. There were significant differences in EIR use by district in both countries.Discussion:The results highlight the importance of organizational and behavioral factors in explaining sustained EIR use. As EIRs are introduced in new settings, we recommend indicators of engagement and use be built directly into the system so they can be routinely monitored, and course corrections can be implemented as needed.