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Global Health: Science and Practice
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Global Health: Science and Practice

Dedicated to what works in global health programs

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Latest Articles

  • Open Access
    Response to “A False Dichotomy: RCTs and Their Contributions to Evidence-Based Public Health”
    James D Shelton
    Global Health: Science and Practice March 2015, 3(1):141-143; https://doi.org/10.9745/GHSP-D-15-00045

    While randomized controlled trials (RCTs) can and do make valuable contributions, they also have severe limitations, including in answering the basic question of “Does it work?” and, even more so, in steering how to proceed with complex public health programming at scale. They deserve no exalted position in the pantheon of methodologies for evidence-based public health.

  • Open Access
    ARVs: The Next Generation. Going Boldly Together to New Frontiers of HIV Treatment
    Matthew Barnhart and James D Shelton
    Global Health: Science and Practice March 2015, 3(1):1-11; https://doi.org/10.9745/GHSP-D-14-00243

    New antiretrovirals (ARVs), particularly the potentially “game-changing” ARV dolutegravir, offer major potential to meet the compelling need for simpler and better HIV treatment for tens of millions of people in the coming decade. Advantages include substantially lower manufacturing cost, fewer side effects, and less risk of resistance. But key obstacles must be addressed in order to develop and introduce new ARVs in specific combinations optimized for the needs of low- and middle-income countries. Strong leadership will be essential from the global health community to nurture more focused collaboration between the private and public sectors.

  • Open Access
    Delivering High-Quality Family Planning Services in Crisis-Affected Settings II: Results
    Dora Ward Curry, Jesse Rattan, Shuyuan Huang and Elizabeth Noznesky
    Global Health: Science and Practice March 2015, 3(1):25-33; https://doi.org/10.9745/GHSP-D-14-00112

    A family planning program in 5 crisis-affected settings reached more than 52,000 new contraceptive users in just 2.5 years. Long-acting reversible contraceptives (LARCs) made up 61% of the method mix, with implants predominating in most countries. IUD use also increased over time as the program intensified its efforts to improve provider skills and user awareness. These findings demonstrate the strong popularity of LARCs and the feasibility of providing them in fragile settings even though they require more training and infrastructure support than short-acting methods.

  • Open Access
    Stunning Popularity of LARCs With Good Access and Quality: A Major Opportunity to Meet Family Planning Needs
    Global Health: Science and Practice March 2015, 3(1):12-13; https://doi.org/10.9745/GHSP-D-15-00044

    Given true choice, a very high proportion of women, perhaps most, would select one of the long-acting reversible contraceptives (LARCs)—implants or IUDs—for contraception. If implemented on a wide scale, it would not only drastically alter the current method mix but also serve client needs much better and prevent unintended pregnancy more successfully.

  • Open Access
    Trends in the Contraceptive Method Mix in Low- and Middle-Income Countries: Analysis Using a New “Average Deviation” Measure
    John Ross, Jill Keesbury and Karen Hardee
    Global Health: Science and Practice March 2015, 3(1):34-55; https://doi.org/10.9745/GHSP-D-14-00199

    Applying a standard measure of the method mix evenness suggests 4 patterns among 15 countries moving toward a more balanced mix: (1) rise of one previously underrepresented or new method, (2) replacement of traditional with modern methods, (3) continued but declining domination by a single method, and (4) general movement toward a balanced mix. Improving availability of underutilized or new methods can improve the method mix, although better implementation of more popular methods might increase contraceptive use more expeditiously.

  • Open Access
    Predictors of Workforce Retention Among Malawian Nurse Graduates of a Scholarship Program: A Mixed-Methods Study
    Kelly Schmiedeknecht, Melanie Perera, Ellen Schell, Joyce Jere, Elizabeth Geoffroy and Sally Rankin
    Global Health: Science and Practice March 2015, 3(1):85-96; https://doi.org/10.9745/GHSP-D-14-00170

    Several non-remuneration strategies may help improve retention of public-sector nurses: availability of supplies, adequate housing, advancement opportunities, and a positive work environment. A scholarship program with close follow-up of graduates may also help improve retention.

  • Open Access
    Delivering High-Quality Family Planning Services in Crisis-Affected Settings I: Program Implementation
    Dora Ward Curry, Jesse Rattan, Jean Jose Nzau and Kamlesh Giri
    Global Health: Science and Practice March 2015, 3(1):14-24; https://doi.org/10.9745/GHSP-D-14-00164

    Extending access to a wide variety of contraceptive methods, including long-acting reversible methods, is feasible in crisis-affected countries by focusing on best practices such as competency-based training, supply chain support, systematic supervision, and community mobilization. Prudent use of data helps drive program improvements.

  • Open Access
    Successful Proof of Concept of Family Planning and Immunization Integration in Liberia
    Chelsea M Cooper, Rebecca Fields, Corinne I Mazzeo, Nyapu Taylor, Anne Pfitzer, Mary Momolu and Cuallau Jabbeh-Howe
    Global Health: Science and Practice March 2015, 3(1):71-84; https://doi.org/10.9745/GHSP-D-14-00156

    Mobilizing vaccinators to provide mothers key family planning information and referrals to co-located, same-day family planning services was feasible in resource-limited areas of Liberia, leading to substantial increases in contraceptive use. Conversely, impact on immunization rates was less clear, but at a minimum there was no decrease in doses administered.

  • Open Access
    A Resource Planning Analysis of District Hospital Surgical Services in the Democratic Republic of the Congo
    Melanie Sion, Dheepa Rajan, Hyppolite Kalambay, Jean-Pierre Lokonga, Joseph Bulakali, Mathias Mossoko, Dieudonne Kwete, Gerard Schmets, Edward Kelley, Tarcisse Elongo, Luis Sambo and Meena Cherian
    Global Health: Science and Practice March 2015, 3(1):56-70; https://doi.org/10.9745/GHSP-D-14-00165

    District hospitals in the DRC, on average, could not provide 21% of lifesaving surgical interventions due to deficiencies in basic infrastructure and essential surgical equipment and supplies. Surgery's important health impact and proportionally low service delivery budget argue for greater emphasis on surgical interventions, including for obstetric care.

  • You have access
    Caution on corticosteroids for preterm delivery: learning from missteps
    Stephen Hodgins
    Global Health: Science and Practice December 2014, 2(4):371-373; https://doi.org/10.9745/GHSP-D-14-00197

    An important new study in lower-level health facilities in low- and middle-income countries found an increased risk of neonatal deaths with corticosteroid use in pregnant women with imminent preterm birth, in contrast with the positive results previously found in high-income countries. The surprising finding demonstrates that context matters. The increase appears largely due to steroids administered in cases that were not actually preterm, probably due to inaccurate pregnancy dating and challenges with diagnostic capacity. Promoting public health often requires decisions based on less-than-perfect evidence, but we must be vigilant about gathering and assessing new evidence and ready to change strategies.

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