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COMMENTARY
Open Access

Novel Approaches to Postnatal Prophylaxis to Eliminate Vertical Transmission of HIV

Theodore Ruel, Martina Penazzato, Jennifer M. Zech, Moherndran Archary, Tim R. Cressey, Ameena Goga, Joseph Harwell, Raphael J. Landovitz, Maria Grazia Lain, Marc Lallemant, Eleanor Namusoke-Magongo, Irene Mukui, Sallie R. Permar, Andrew J. Prendergast, Roger Shapiro and Elaine J. Abrams
Global Health: Science and Practice April 2023, 11(2):e2200401; https://doi.org/10.9745/GHSP-D-22-00401
Theodore Ruel
aUniversity of California, San Francisco, San Francisco, CA, USA.
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Martina Penazzato
bWorld Health Organization, Geneva, Switzerland.
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Jennifer M. Zech
cICAP at Columbia University, Mailman School of Public Health, Columbia University, NY, USA.
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Moherndran Archary
dUniversity of KwaZulu-Natal, Durban, South Africa.
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Tim R. Cressey
eAMS-IRD Research Collaboration, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, Thailand.
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Ameena Goga
fHIV and other Infectious Diseases Research Unit, South African Medical Research Council, Cape Town, South Africa.
gDepartment of Paediatrics and Child Health, University of Pretoria, South Africa.
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Joseph Harwell
hClinton Health Access Initiative, Boston, MA, USA.
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Raphael J. Landovitz
iUCLA Center for Clinical AIDS Research and Education, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.
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Maria Grazia Lain
jFundação Ariel Glaser contra o SIDA Pediátrico, Maputo, Mozambique.
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Marc Lallemant
kAMS-PHPT Research Collaboration, Chiang Mai University, Chiang Mia, Thailand.
lPenta Foundation Italy, Padova, Italy.
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Eleanor Namusoke-Magongo
mPaediatric and Adolescent HIV Care Treatment Branch, Ministry of Health, Kampala, Uganda.
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Irene Mukui
nDrugs for Neglected Diseases Initiative, Nairobi, Kenya.
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Sallie R. Permar
oDepartment of Pediatrics, Weill Cornell Medicine, New York, NY, USA.
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Andrew J. Prendergast
pQueen Mary University of London, London, United Kingdom.
qZvitambo Institute for Maternal and Child Health Research, Harare, Zimbabwe.
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Roger Shapiro
rDepartment of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
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Elaine J. Abrams
cICAP at Columbia University, Mailman School of Public Health, Columbia University, NY, USA.
sVagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA.
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Global Health: Science and Practice: 11 (2)
Global Health: Science and Practice
Vol. 11, No. 2
April 28, 2023
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Novel Approaches to Postnatal Prophylaxis to Eliminate Vertical Transmission of HIV
Theodore Ruel, Martina Penazzato, Jennifer M. Zech, Moherndran Archary, Tim R. Cressey, Ameena Goga, Joseph Harwell, Raphael J. Landovitz, Maria Grazia Lain, Marc Lallemant, Eleanor Namusoke-Magongo, Irene Mukui, Sallie R. Permar, Andrew J. Prendergast, Roger Shapiro, Elaine J. Abrams
Global Health: Science and Practice Apr 2023, 11 (2) e2200401; DOI: 10.9745/GHSP-D-22-00401

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Novel Approaches to Postnatal Prophylaxis to Eliminate Vertical Transmission of HIV
Theodore Ruel, Martina Penazzato, Jennifer M. Zech, Moherndran Archary, Tim R. Cressey, Ameena Goga, Joseph Harwell, Raphael J. Landovitz, Maria Grazia Lain, Marc Lallemant, Eleanor Namusoke-Magongo, Irene Mukui, Sallie R. Permar, Andrew J. Prendergast, Roger Shapiro, Elaine J. Abrams
Global Health: Science and Practice Apr 2023, 11 (2) e2200401; DOI: 10.9745/GHSP-D-22-00401
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  • Article
    • INTRODUCTION
    • WHAT IS THE EVIDENCE BASE FOR CURRENT APPROACHES TO POSTNATAL PROPHYLAXIS?
    • WHAT ARE THE CHALLENGES SPECIFIC TO STUDYING PHARMACOKINETICS AND DETERMINING DOSING FOR NEONATES?
    • WHAT CAN WE LEARN FROM STUDIES OF HIV ANTIRETROVIRAL PROPHYLAXIS IN ADULTS ABOUT TARGET PRODUCT PROFILES?
    • WHAT IS THE POTENTIAL ROLE OF PASSIVE IMMUNIZATION IN POSTNATAL PROPHYLAXIS?
    • DO POSTNATAL PROPHYLAXIS STRATEGIES NEED TO BE RISK STRATIFIED?
    • SHOULD ALL INFANTS RECEIVE POSTNATAL PROPHYLAXIS WHILE BREASTFEEDING?
    • WHAT ARE POTENTIAL APPROACHES TO POSTNATAL PROPHYLAXIS IN THE NEAR AND FAR FUTURE?
    • CONCLUSION
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  • Recognizing and Addressing the Contraceptive Hesitancy-Acceptability Continuum: Adopting Lessons Learned From the Immunization Field
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