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ORIGINAL ARTICLE
Open Access

What Distinguishes Women Who Choose to Self-Inject? A Prospective Cohort Study of Subcutaneous Depot Medroxyprogesterone Acetate Users in Ghana

Dela Nai, Elizabeth Tobey, Kamil Fuseini, Patrick Kuma-Aboagye and Aparna Jain
Global Health: Science and Practice February 2022, 10(1):e2100534; https://doi.org/10.9745/GHSP-D-21-00534
Dela Nai
aPopulation Council, Accra, Ghana.
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  • For correspondence: dnai{at}popcouncil.org
Elizabeth Tobey
bPopulation Council, Washington, DC, USA.
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Kamil Fuseini
aPopulation Council, Accra, Ghana.
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Patrick Kuma-Aboagye
cGhana Health Service, Accra, Ghana.
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Aparna Jain
bPopulation Council, Washington, DC, USA.
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    FIGURE

    Sankey Diagram of Patterns of DMPA-SC Mode of Injection Administration, Discontinuation, and Lost to Follow-Up Over the 3 Injection Periods (n=378)

    Abbreviation: DMPA-SC, subcutaneous injection of depot medroxyprogesterone acetate.

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    TABLE 1

    Characteristics of Women at First Injection Who Continued Using DMPA-SC at Third Injection, Ghana (n=378)

    No. (%)
    Age range, years
     18–24124 (32.8)
     25–2998 (25.9)
     30–3472 (19.0)
     35 and older84 (22.2)
    Marital status
     Never married114 (30.2)
     Ever married/in union264 (69.8)
    Number of living children
     None57 (15.1)
     1-2162 (42.9)
     3+159 (42.1)
    Region/residence
     Ashanti rural67 (17.7)
     Ashanti urban93 (24.6)
     Volta rural77 (20.4)
     Volta urban141 (37.3)
    Education
     No education31 (8.2)
     Primary70 (18.5)
     Junior secondary school/junior high school189 (50.0)
     Senior secondary school/senior high school or higher88 (23.3)
    Employment status
     Not currently working148 (39.2)
     Currently working230 (60.8)
    Previously used FP
     New FP user166 (43.9)
     Previous DMPA-IM user172 (45.5)
     Previous user of other method40 (10.6)
    Receipt of MIIplus
     Did not receive full MIIplus98 (25.9)
     Received full MIIplus280 (74.1)
    Mode of administration of third injection
     Provider-administered104 (27.5)
     Self-administered274 (72.5)
      At the facility (on-site)96 (25.4)
      At home178 (47.1)
    • Abbreviations: DMPA-IM, intramuscular injection of depot medroxyprogesterone acetate; DMPA-SC, subcutaneous injection of depot medroxyprogesterone acetate; FP, family planning; MIIplus, revised method information index.

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    TABLE 2.

    Mode of DMPA-SC Injection Administration at Third Injection by Respondent Characteristics, Ghana (n=378)

    No.Provider-Administered, %Self-Injection, %
    Age range, yearsa
     18–2412421.878.2
     25–299825.574.5
     30–347223.676.4
     35 and older8441.758.3
    Marital statusa
     Never married11419.380.7
     Ever married/in union26431.168.9
    Number of living children
     None5717.582.5
     1–216225.974.1
     3+15932.767.3
    Region/residence
     Ashanti rural6717.982.1
     Ashanti urban9268.831.2
     Volta rural779.190.9
     Volta urban14114.985.1
    Education
     No education3135.564.5
     Primary7021.478.6
     Junior secondary school/junior high school18930.769.3
     Senior secondary school/senior high school or higher8822.777.3
    Employment status
     Not currently working14822.377.7
     Currently working23030.969.1
    Previously used FPb
     New FP user16618.781.3
     Previous DMPA-IM user17237.262.8
     Previous user of other method4022.577.5
    Receipt of MIIplusc
     Did not receive full MIIplus9843.956.1
     Received full MIIplus28021.878.2
    Total37827.572.5
    • Abbreviations: DMPA-IM, intramuscular injection of depot medroxyprogesterone acetate; DMPA-SC, subcutaneous injection of depot medroxyprogesterone acetate; FP, family planning; MIIplus, revised method information index.

    • ↵a P<.05.

    • ↵b P<.01.

    • ↵c P<.001.

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    TABLE 3.

    Adjusted Odds Ratios of DMPA-SC Self-Injection at Third Injection, Ghana (n=378)a

    Adjusted Odds Ratio95% Confidence Interval
    Age range, years
     18–24ref
     25–291.230.56, 2.69
     30–341.350.49, 3.70
     35 and older0.640.25, 1.60
    Marital status
     Ever married/in unionref
     Never married2.32b1.05, 5.14
    Number of living children
     NoneRef
     1–2 children1.210.44, 3.29
     3+ children1.390.44, 4.45
    Education
     No education0.930.35, 2.50
     Primary1.190.55, 2.60
     Junior secondary school/junior high schoolRef
     Senior secondary school/senior high school or higher2.69b1.21, 6.01
    Employment status
     Not currently workingRef
     Currently working1.580.83, 3.00
    Previously used family planning
     New FP user2.51c1.31, 4.80
     Previous DMPA-IM userRef
     Previous user of other method2.680.98, 7.34
    Receipt of MIIplus
     Did not receive full MIIplusRef
     Received full MIIplus0.850.42, 1.71
    • Abbreviations: DMPA-IM, intramuscular injection of depot medroxyprogesterone acetate; DMPA-SC, subcutaneous injection of depot medroxyprogesterone acetate; FP, family planning; MIIplus, revised method information index.

    • ↵a Adjusted for clustering at the region/residence level.

    • ↵b P<.05.

    • ↵c P<.01.

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Global Health: Science and Practice: 10 (1)
Global Health: Science and Practice
Vol. 10, No. 1
February 28, 2022
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What Distinguishes Women Who Choose to Self-Inject? A Prospective Cohort Study of Subcutaneous Depot Medroxyprogesterone Acetate Users in Ghana
Dela Nai, Elizabeth Tobey, Kamil Fuseini, Patrick Kuma-Aboagye, Aparna Jain
Global Health: Science and Practice Feb 2022, 10 (1) e2100534; DOI: 10.9745/GHSP-D-21-00534

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What Distinguishes Women Who Choose to Self-Inject? A Prospective Cohort Study of Subcutaneous Depot Medroxyprogesterone Acetate Users in Ghana
Dela Nai, Elizabeth Tobey, Kamil Fuseini, Patrick Kuma-Aboagye, Aparna Jain
Global Health: Science and Practice Feb 2022, 10 (1) e2100534; DOI: 10.9745/GHSP-D-21-00534
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