Early striatal dendrite deficits followed by neuron loss with advanced age in the absence of anterograde cortical brain-derived neurotrophic factor
ZC Baquet, JA Gorski, KR Jones - Journal of Neuroscience, 2004 - Soc Neuroscience
Brain-derived neurotrophic factor (BDNF), a member of the neurotrophin family, modulates
neuronal survival, differentiation, and synaptic function. Reduced BDNF expression in the …
neuronal survival, differentiation, and synaptic function. Reduced BDNF expression in the …
Brain-derived neurotrophic factor is required for the establishment of the proper number of dopaminergic neurons in the substantia nigra pars compacta
ZC Baquet, PC Bickford, KR Jones - Journal of Neuroscience, 2005 - Soc Neuroscience
Brain-derived neurotrophic factor (BDNF) has been implicated in regulating neuronal survival,
differentiation, and synaptic plasticity. Reduced expression of BDNF within the substantia …
differentiation, and synaptic plasticity. Reduced expression of BDNF within the substantia …
Expression profiling of Huntington's disease models suggests that brain-derived neurotrophic factor depletion plays a major role in striatal degeneration
AD Strand, ZC Baquet, AK Aragaki… - Journal of …, 2007 - Soc Neuroscience
Many pathways have been proposed as contributing to Huntington's disease (HD)
pathogenesis, but generally the in vivo effects of their perturbation have not been compared with …
pathogenesis, but generally the in vivo effects of their perturbation have not been compared with …
A comparison of model-based (2D) and design-based (3D) stereological methods for estimating cell number in the substantia nigra pars compacta (SNpc) of the …
ZC Baquet, D Williams, J Brody, RJ Smeyne - Neuroscience, 2009 - Elsevier
The substantia nigra pars compacta (SNpc) is a compact brain structure that contains a variable
distribution of cells in both medial to lateral and rostral to caudal dimensions. The SNpc …
distribution of cells in both medial to lateral and rostral to caudal dimensions. The SNpc …
Scalable signaling mediated by T cell antigen receptor–CD3 ITAMs ensures effective negative selection and prevents autoimmunity
…, KD Eder, CJ Workman, KL Boyd, Z Baquet… - Nature …, 2008 - nature.com
The T cell antigen receptor (TCR)-CD3 complex is unique in having ten cytoplasmic
immunoreceptor tyrosine-based activation motifs (ITAMs). The physiological importance of this high …
immunoreceptor tyrosine-based activation motifs (ITAMs). The physiological importance of this high …
[HTML][HTML] Conservation of regional gene expression in mouse and human brain
AD Strand, AK Aragaki, ZC Baquet, A Hodges… - PLoS …, 2007 - journals.plos.org
Many neurodegenerative diseases have a hallmark regional and cellular pathology. Gene
expression analysis of healthy tissues may provide clues to the differences that distinguish …
expression analysis of healthy tissues may provide clues to the differences that distinguish …
Central nervous system destruction mediated by glutamic acid decarboxylase-specific CD4+ T cells
AR Burton, Z Baquet, GS Eisenbarth… - The Journal of …, 2010 - journals.aai.org
High titers of autoantibodies against glutamic acid decarboxylase (GAD) 65 are commonly
observed in patients suffering from type 1 diabetes as well as stiff-person syndrome (SPS), a …
observed in patients suffering from type 1 diabetes as well as stiff-person syndrome (SPS), a …
Expression of neurotrophin‐3 in the mouse forebrain: Insights from a targeted LacZ reporter
AJ Vigers, ZC Baquet, KR Jones - Journal of Comparative …, 2000 - Wiley Online Library
To obtain insights into the expression of neurotrophin-3 (NT-3) in the mouse, we have utilized
mice in which the Escherichia coli lacZ gene is integrated into the neurotrophin-3 locus (NT…
mice in which the Escherichia coli lacZ gene is integrated into the neurotrophin-3 locus (NT…
[HTML][HTML] Leveraging the power of knowledge management to transform global health and development
…, V Mitchell, M D'Adamo, Z Baquet - … Health: Science and …, 2015 - ghspjournal.org
Good knowledge is essential to prevent disease and improve health. Knowledge management
(KM) provides a systematic process and tools to promote access to and use of knowledge …
(KM) provides a systematic process and tools to promote access to and use of knowledge …
Loss of neurotrophin-3 from smooth muscle disrupts vagal gastrointestinal afferent signaling and satiation
EA Fox, JE Biddinger, ZC Baquet… - American Journal …, 2013 - journals.physiology.org
A large proportion of vagal afferents are dependent on neurotrophin-3 (NT-3) for survival. NT-3
is expressed in developing gastrointestinal (GI) smooth muscle, a tissue densely …
is expressed in developing gastrointestinal (GI) smooth muscle, a tissue densely …