User profiles for R. Folz
Rodney FolzCase Western Reserve University Verified email at case.edu Cited by 10595 |
Superoxide dismutase multigene family: a comparison of the CuZn-SOD (SOD1), Mn-SOD (SOD2), and EC-SOD (SOD3) gene structures, evolution, and expression
Superoxide dismutases are an ubiquitous family of enzymes that function to efficiently
catalyze the dismutation of superoxide anions. Three unique and highly compartmentalized …
catalyze the dismutation of superoxide anions. Three unique and highly compartmentalized …
Extracellular superoxide dismutase and cardiovascular disease
Excessive production and/or inadequate removal of reactive oxygen species, especially
superoxide anion (O 2 •− ), have been implicated in the pathogenesis of many cardiovascular …
superoxide anion (O 2 •− ), have been implicated in the pathogenesis of many cardiovascular …
Radiation-induced lung injury
LB Marks, X Yu, Z Vujaskovic, W Small Jr, R Folz… - Seminars in radiation …, 2003 - Elsevier
Radiation therapy (RT) for thoracic-region tumors often causes lung injury. The incidence of
lung toxicity depends on the method of assessment (eg, radiographs, patient’s symptoms, or …
lung toxicity depends on the method of assessment (eg, radiographs, patient’s symptoms, or …
[HTML][HTML] Myeloablative autologous stem-cell transplantation for severe scleroderma
Background Despite current therapies, diffuse cutaneous systemic sclerosis (scleroderma)
often has a devastating outcome. We compared myeloablative CD34+ selected autologous …
often has a devastating outcome. We compared myeloablative CD34+ selected autologous …
An official American Thoracic Society research statement: noninfectious lung injury after hematopoietic stem cell transplantation: idiopathic pneumonia syndrome
…, JA Belperio, IY Haddad, RJ Folz… - American journal of …, 2011 - atsjournals.org
Rationale: Acute lung dysfunction of noninfectious etiology, known as idiopathic pneumonia
syndrome (IPS), is a severe complication following hematopoietic stem cell transplantation (…
syndrome (IPS), is a severe complication following hematopoietic stem cell transplantation (…
Apoptosis and delayed neuronal damage after carbon monoxide poisoning in the rat
Delayed neurological damage after CO hypoxia was studied in rats to determine whether
programmed cell death (PCD), in addition to necrosis, is involved in neuronal death. In rats …
programmed cell death (PCD), in addition to necrosis, is involved in neuronal death. In rats …
Hypoxic pulmonary hypertension: role of superoxide and NADPH oxidase (gp91phox)
Chronic exposure to low-O 2 tension induces pulmonary arterial hypertension (PAH), which
is characterized by vascular remodeling and enhanced vasoreactivity. Recent evidence …
is characterized by vascular remodeling and enhanced vasoreactivity. Recent evidence …
[HTML][HTML] Extracellular superoxide dismutase in the airways of transgenic mice reduces inflammation and attenuates lung toxicity following hyperoxia
RJ Folz, AM Abushamaa… - The Journal of clinical …, 1999 - Am Soc Clin Investig
Extracellular superoxide dismutase (EC-SOD, or SOD3) is the major extracellular antioxidant
enzyme in the lung. To study the biologic role of EC-SOD in hyperoxic-induced pulmonary …
enzyme in the lung. To study the biologic role of EC-SOD in hyperoxic-induced pulmonary …
[HTML][HTML] Bronchodilators in tobacco-exposed persons with symptoms and preserved lung function
Background Many persons with a history of smoking tobacco have clinically significant
respiratory symptoms despite an absence of airflow obstruction as assessed by spirometry. They …
respiratory symptoms despite an absence of airflow obstruction as assessed by spirometry. They …
Extracellular superoxide dismutase (SOD3): tissue-specific expression, genomic characterization, and computer-assisted sequence analysis of the human EC SOD …
We have isolated and characterized over 10,000 bp of the human EC SOD gene (SOD3 or
EC 1.15.1.1) and its 5′- and 3′-flanking regions. Human genomic Southern blot analysis …
EC 1.15.1.1) and its 5′- and 3′-flanking regions. Human genomic Southern blot analysis …