[HTML][HTML] Prevention of HIV-1 infection with early antiretroviral therapy
…, N Kumarasamy, JG Hakim… - New England journal …, 2011 - Mass Medical Soc
Background Antiretroviral therapy that reduces viral replication could limit the transmission
of human immunodeficiency virus type 1 (HIV-1) in serodiscordant couples. Methods In nine …
of human immunodeficiency virus type 1 (HIV-1) in serodiscordant couples. Methods In nine …
[HTML][HTML] Antiretroviral therapy for the prevention of HIV-1 transmission
…, N Kumarasamy, JG Hakim… - … England Journal of …, 2016 - Mass Medical Soc
Background An interim analysis of data from the HIV Prevention Trials Network (HPTN) 052
trial showed that antiretroviral therapy (ART) prevented more than 96% of genetically linked …
trial showed that antiretroviral therapy (ART) prevented more than 96% of genetically linked …
Effects of early versus delayed initiation of antiretroviral treatment on clinical outcomes of HIV-1 infection: results from the phase 3 HPTN 052 randomised controlled …
…, T Gamble, N Kumarasamy, JG Hakim… - The Lancet infectious …, 2014 - thelancet.com
Background Use of antiretroviral treatment for HIV-1 infection has decreased AIDS-related
morbidity and mortality and prevents sexual transmission of HIV-1. However, the best time to …
morbidity and mortality and prevents sexual transmission of HIV-1. However, the best time to …
Impact of HIV infection on meningitis in Harare, Zimbabwe: a prospective study of 406 predominantly adult patients
JG Hakim, IT Gangaidzo, RS Heyderman, J Mielke… - Aids, 2000 - journals.lww.com
Results Four-hundred and six predominantly adult (95% were aged≥ 18 years) patients
were suspected to have meningitis. Of the 200 patients confirmed to have meningitis, 89 (45%) …
were suspected to have meningitis. Of the 200 patients confirmed to have meningitis, 89 (45%) …
Early versus delayed initiation of antiretroviral therapy for concurrent HIV infection and cryptococcal meningitis in sub-saharan Africa
…, M Kurangwa, P Gona, JG Hakim - Clinical Infectious …, 2010 - academic.oup.com
Background . Cryptococcal meningitis (CM) remains a leading cause of acquired
immunodeficiency syndrome-related death in sub-Saharan Africa. The timing of the initiation of …
immunodeficiency syndrome-related death in sub-Saharan Africa. The timing of the initiation of …
[HTML][HTML] The magnitude of loss to follow-up of HIV-exposed infants along the prevention of mother-to-child HIV transmission continuum of care: a systematic review …
EL Sibanda, IVD Weller, JG Hakim, FM Cowan - Aids, 2013 - journals.lww.com
Methods: Eligible publications reported infant LTFU outcomes from standard care PMTCT
programs (not intervention studies) at any stage of the cascade. Literature searches were …
programs (not intervention studies) at any stage of the cascade. Literature searches were …
Analysis of genetic linkage of HIV from couples enrolled in the HIV Prevention Trials Network 052 trial
…, JG Hakim, S Chariyalertsak, G De Bruyn… - The Journal of …, 2011 - academic.oup.com
Background. The HIV Prevention Trials Network (HPTN) 052 trial demonstrated that early
initiation of antiretroviral therapy (ART) reduces human immunodeficiency virus (HIV) …
initiation of antiretroviral therapy (ART) reduces human immunodeficiency virus (HIV) …
Cryptococcal meningitis in human immunodeficiency virus-infected patients in Harare, Zimbabwe
RS Heyderman, IT Gangaidzo, JG Hakim… - Clinical infectious …, 1998 - academic.oup.com
A prospective observational study was conducted over a 10-month period to determine the
clinical and laboratory manifestations of cryptococcal meningitis in Zimbabwe, a country …
clinical and laboratory manifestations of cryptococcal meningitis in Zimbabwe, a country …
Undisclosed antiretroviral drug use in a multinational clinical trial (HIV Prevention Trials Network 052)
…, J Kumwenda, JG Hakim… - The Journal of …, 2013 - academic.oup.com
The HIV Prevention Trials Network 052 study enrolled serodiscordant couples. Index
participants infected with human immunodeficiency virus reported no prior antiretroviral (ARV) …
participants infected with human immunodeficiency virus reported no prior antiretroviral (ARV) …
[HTML][HTML] Lopinavir plus nucleoside reverse-transcriptase inhibitors, lopinavir plus raltegravir, or lopinavir monotherapy for second-line treatment of HIV (EARNEST) …
JG Hakim, J Thompson, C Kityo, A Hoppe… - The Lancet Infectious …, 2018 - thelancet.com
Background Millions of HIV-infected people worldwide receive antiretroviral therapy (ART)
in programmes using WHO-recommended standardised regimens. Recent WHO guidelines …
in programmes using WHO-recommended standardised regimens. Recent WHO guidelines …