User profiles for Douglas Taylor
Douglas TaylorUniversity of Virginia Verified email at virginia.edu Cited by 7766 |
[HTML][HTML] Vesiclepedia: a compendium for extracellular vesicles with continuous community annotation
…, P Siljander, A Stensballe, W Stoorvogel, D Taylor… - PLoS …, 2012 - journals.plos.org
Extracellular vesicles (EVs) are membraneous vesicles released by a variety of cells into
their microenvironment. Recent studies have elucidated the role of EVs in intercellular …
their microenvironment. Recent studies have elucidated the role of EVs in intercellular …
Retracted: microRNA signatures of tumor-derived exosomes as diagnostic biomarkers of ovarian cancer
DD Taylor, C Gercel-Taylor - 2008 - Elsevier
OBJECTIVES: Most ovarian cancer patients are diagnosed at an advanced stage (67%) and
prospects for significant improvement in survival reside in early diagnosis. While expression …
prospects for significant improvement in survival reside in early diagnosis. While expression …
Effectiveness and safety of tenofovir gel, an antiretroviral microbicide, for the prevention of HIV infection in women
…, N Arulappan, M Mlotshwa, L Morris, D Taylor… - science, 2010 - science.org
The Centre for the AIDS Program of Research in South Africa (CAPRISA) 004 trial assessed
the effectiveness and safety of a 1% vaginal gel formulation of tenofovir, a nucleotide …
the effectiveness and safety of a 1% vaginal gel formulation of tenofovir, a nucleotide …
Exosomal microRNA: a diagnostic marker for lung cancer
G Rabinowits, C Gerçel-Taylor, JM Day, DD Taylor… - Clinical lung cancer, 2009 - Elsevier
Purpose To date, there is no screening test for lung cancer shown to affect overall mortality.
MicroRNAs (miRNAs) are a class of small noncoding RNA genes found to be abnormally …
MicroRNAs (miRNAs) are a class of small noncoding RNA genes found to be abnormally …
[HTML][HTML] Preexposure prophylaxis for HIV infection among African women
Background Preexposure prophylaxis with antiretroviral drugs has been effective in the
prevention of human immunodeficiency virus (HIV) infection in some trials but not in others. …
prevention of human immunodeficiency virus (HIV) infection in some trials but not in others. …
Defective angiogenesis in mice lacking endoglin
…, BS Brooke, LD Urness, EC Davis, DG Taylor… - Science, 1999 - science.org
Endoglin is a transforming growth factor–β (TGF-β) binding protein expressed on the surface
of endothelial cells. Loss-of-function mutations in the human endoglin gene ENGcause …
of endothelial cells. Loss-of-function mutations in the human endoglin gene ENGcause …
[HTML][HTML] Micro-Raman spectroscopy detects individual neoplastic and normal hematopoietic cells
Current methods for identifying neoplastic cells and discerning them from their normal
counterparts are often nonspecific, slow, biologically perturbing, or a combination thereof. Here, …
counterparts are often nonspecific, slow, biologically perturbing, or a combination thereof. Here, …
Methods of isolating extracellular vesicles impact down-stream analyses of their cargoes
DD Taylor, S Shah - Methods, 2015 - Elsevier
Viable tumor cells actively release vesicles into the peripheral circulation and other biologic
fluids, which exhibit proteins and RNAs characteristic of that cell. Our group demonstrated …
fluids, which exhibit proteins and RNAs characteristic of that cell. Our group demonstrated …
Fas ligand–positive membranous vesicles isolated from sera of patients with oral cancer induce apoptosis of activated T lymphocytes
JW Kim, E Wieckowski, DD Taylor, TE Reichert… - Clinical Cancer …, 2005 - AACR
Objective: In patients with oral squamous cell carcinoma, a high proportion of T cells in the
tumor undergo apoptosis, which correlates with Fas ligand (FasL) expression on tumor cells. …
tumor undergo apoptosis, which correlates with Fas ligand (FasL) expression on tumor cells. …
[HTML][HTML] Rapid evolution of enormous, multichromosomal genomes in flowering plant mitochondria with exceptionally high mutation rates
Genome size and complexity vary tremendously among eukaryotic species and their
organelles. Comparisons across deeply divergent eukaryotic lineages have suggested that …
organelles. Comparisons across deeply divergent eukaryotic lineages have suggested that …