Interventions to significantly improve service uptake and retention of HIV‐positive pregnant women and HIV‐exposed infants along the prevention of mother‐to‐child …

AC Vrazo, J Firth, A Amzel, R Sedillo… - Tropical Medicine & …, 2018 - Wiley Online Library
Objectives Despite the success of Prevention of Mother‐to‐Child Transmission of HIV ( PMTCT
) programmes, low uptake of services and poor retention pose a formidable challenge to …

[HTML][HTML] Eliminating mother-to-child transmission of HIV by 2030: 5 strategies to ensure continued progress

AC Vrazo, D Sullivan, BR Phelps - Global Health: Science and …, 2018 - ghspjournal.org
To keep up momentum in preventing mother-to-child transmission we propose: (1) advocating
for greater political and financial commitment; (2) targeting high-risk populations such as …

Adapting HIV services for pregnant and breastfeeding women, infants, children, adolescents and families in resource‐constrained settings during the COVID‐19 …

AC Vrazo, R Golin, NB Fernando… - Journal of the …, 2020 - Wiley Online Library
Introduction The COVID‐19 pandemic has impacted global health service delivery, including
provision of HIV services. Countries with high HIV burden are balancing the need to …

[HTML][HTML] Epstein-Barr virus LMP2A reduces hyperactivation induced by LMP1 to restore normal B cell phenotype in transgenic mice

AC Vrazo, M Chauchard, N Raab-Traub… - PLoS …, 2012 - journals.plos.org
Epstein-Barr virus (EBV) latently infects most of the human population and is strongly
associated with lymphoproliferative disorders. EBV encodes several latency proteins affecting B …

Live cell evaluation of granzyme delivery and death receptor signaling in tumor cells targeted by human natural killer cells

AC Vrazo, AE Hontz, SK Figueira… - Blood, The Journal …, 2015 - ashpublications.org
Growing interest in natural killer (NK) cell–based therapy for treating human cancer has
made it imperative to develop new tools to measure early events in cell death. We recently …

[HTML][HTML] Integration of neonatal and child health interventions with pediatric HIV interventions in global health

…, S Konopka, R Golin, AC Vrazo - … Journal of MCH and …, 2018 - ncbi.nlm.nih.gov
Methods: Databases were systematically searched for peer-reviewed studies. Interventions
of interest were HIV services integrated with: neonatal/child services for children< 5 years, …

SMAC mimetic in combination with HDACi effectively release brakes on cell death of chronic myeloid leukemia K562 cells accelerating ligand-mediated apoptosis.

AE Hontz, AC Vrazo, SK Figueira… - The Journal of …, 2016 - journals.aai.org
Enthusiasm for immunotherapy has reached an all-time high within the last year due to
remarkable clinical outcomes using strategies directed at activating T cells. The mechanisms by …

Epstein-Barr Virus Latent Membrane Protein 2A Modulates The Function of Latent Membrane Protein 1 In A Model of Viral Latency

ACA Vrazo - 2012 - search.proquest.com
Epstein-Barr virus (EBV) latently infects most of the human population and is strongly associated
with rare lymphoproliferative disorders. EBV encodes several latency proteins including …

Real-time detection of CTL function reveals distinct patterns of caspase activation mediated by Fas versus granzyme B

J Li, SK Figueira, ACA Vrazo, BF Binkowski… - The Journal of …, 2014 - journals.aai.org
Activation of caspase-mediated apoptosis is reported to be a hallmark of both granzyme B–and
Fas-mediated pathways of killing by CTLs; however, the kinetics of caspase activation …

Animal Models of Burkitt's Lymphoma

A Vrazo, M Chauchard, O Cen, R Longnecker - Burkitt's Lymphoma, 2013 - Springer
Animal models are a powerful means for studying the contribution of the Myc proto-oncogene
and Epstein–Barr virus (EBV) to Burkitt’s lymphoma and in the study of potential …