TY - JOUR T1 - Eliminating Mother-to-Child Transmission of HIV by 2030: 5 Strategies to Ensure Continued Progress JF - Global Health: Science and Practice JO - GLOB HEALTH SCI PRACT SP - 249 LP - 256 DO - 10.9745/GHSP-D-17-00097 VL - 6 IS - 2 AU - Alexandra C. Vrazo AU - David Sullivan AU - Benjamin Ryan Phelps Y1 - 2018/06/27 UR - http://www.ghspjournal.org/content/6/2/249.abstract N2 - To keep up momentum in preventing mother-to-child transmission we propose: (1) advocating for greater political and financial commitment; (2) targeting high-risk populations such as adolescent girls and young women; (3) implementing novel service delivery models such as community treatment groups; (4) performing regular viral load monitoring during pregnancy and postpartum to ensure suppression before delivery and during breastfeeding; and (5) harnessing technology in monitoring and evaluation and HIV diagnostics.Over the last 3 decades, prevention of mother-to-child transmission (PMTCT) of HIV programs have been at the forefront of HIV care and treatment innovation. The Global Plan Towards Eliminating New HIV Infections Among Children by 2015 and Keeping Their Mothers Alive, launched in 2011, set a series of ambitious targets for 2015 including the reduction of new HIV infections among children by 90% and AIDS-related maternal mortality by 50% from 2009 through 2015.1 The successful global movement to start all pregnant and breastfeeding women on antiretroviral therapy (ART) regardless of CD4 T-cell count or clinical staging (known as Option B+)2,3 set the stage for the World Health Organization's (WHO's) aptly named “Treat All” guidelines, which eliminated many long-standing barriers to HIV treatment.4 Meanwhile, data from several clinical trials—PROMISE, TEMPRANO, START, and HPTN 052—further demonstrated how outcomes improve with ART initiation at any CD4 T-cell count.5–8 These studies demonstrated lower morbidity and mortality, increased linkages to care, faster immune system reconstitution, and decreased HIV transmission in those starting ART sooner. The rapid scale up of Option B+ to more than 21 countries has demonstrated that programs designed to test and then quickly start treatment in all pregnant and breastfeeding women with HIV lead to increased enrollment, infections averted, and lives saved.9 The elimination of mother-to-child transmission of HIV in Armenia, Belarus, the Caribbean, … ER -