A New World Health Era

Unprecedented economic progress and demands for social protection have engendered an economic transition in health in many low- and middle-income countries, characterized by major increases in domestic health spending and growing national autonomy. At the global level, development assistance is refocusing on fragile states, the poorest communities, and cooperation on global public goods like health security, technical norms, and innovation. Intergovernmental organizations like WHO need the wherewithal and support to provide leadership and to properly advance this new world health era.


AN ECONOMIC TRANSITION IN HEALTH
After centuries of flat incomes per capita, the world has experienced a 20-fold increase in gross domestic product (GDP) during the last 50 years. 6,7The majority of countries that were considered low-income in 1990, including Bolivia, Bangladesh, and the Republic of Congo, have moved to lower-middle or middle-income status. 8ealth spending is very closely correlated with GDP and it accounts for an expanding fraction of any growing economy. 9While that is often a fiscal and political headache for richer countries, for a growing number of lower-income countries the increase in health resources has the potential to cover the average cost per capita of essential lifesaving commodities and services. 9s DAH plateaued in recent years, 1 many lowincome countries saw total health spending grow at 10% per year (based on data from National Health Accounts compiled by USAID in 2015).Public and private domestic resources now dwarf DAH (Figure 1).The growth of health spending, however, follows a surge in the demand for health services that is often met by unregulated private services paid out-of-pocket, an inefficient and regressive form of health financing. 11This transition is linked to the economics of countries at different stages of development.Thus, these changes have already occurred in several countries and may not be complete in others by 2030.

A HISTORICAL PENDULUM IN THE POLITICAL ECONOMY
Political economy is the branch of social science that studies the relationships between individuals and society and between markets and the state. 12The liberal forces galvanized by the Enlightenment, the 18th century philosophical movement in Europe that promoted freedom, fraternity, solidarity, and equality, have brought unprecedented well-being to our civilization, 13 but progress has not been linear.Periodic structural shifts in the political economy, whether arising from global crises or national elections, bring new challenges and opportunities and change the ways in which the health agenda is advanced.
After World War II, with the end of European colonialism, what was known as geographic or "tropical medicine" became firmly established as "international health," with newly created international agencies and new and assertive nations committed to primary health care (Figure 2). 14][17][18] At that time, after the collapse of the Soviet Union, the Washington Consensus-the set of market economic ideas supported by the International Monetary Fund and the World Bank-downplayed national government and promoted neoliberal policies, i.e., a strong market-based approach to globalization, decentralization, and privatization. 19New philanthropy and the AIDS movement were additional ingredients of what became "global health." 20WHO's influence waned 21,22 amidst a plethora of new public-private partnerships advancing donor-supported initiatives against AIDS, tuberculosis, malaria, and vaccine-preventable diseases. 14,23While some experts worried about open-source anarchy and undue influence, 24 these global partnerships contributed to achieving several MDGs.
We are at a new inflexion point.The Great Recession of 2008 caused a reduction in global GDP and global trade for the first time in half a century. 25While markets have recovered since, their failure caused ongoing social pain and revealed severe inequalities, 26 leading to economic insecurity and growing political demand for social protection and popular rejection of globalization. 5,27ational governments are reasserting themselves, in extreme cases with protectionism and xenophobia. 28Countries that responded to the crisis with fiscal austerity have faced a wave of antiestablishment, ethnopopulist elections not seen since the 1930s. 29This creates many domestic problems of its own and pushes back against the international cooperation and altruism that characterized the golden era of global health.In the long run, populism is no substitute for sound governance and it carries risks. 30Good technical and political leadership is needed to address the underlying economic inequalities responsible for the social turmoil seen in many countries.

A NEW WORLD HEALTH ERA?
Economic growth and increasing health spending in many "developing" countries, along with stagnant DAH and a wave of populist policies, pave the way for a number of profound changes in our field (Table ).At the national level, there will be more country ownership and domestic resource mobilization (DRM), with an increasingly feasible possibility of achieving universal health coverage (UHC).At the global level, the power of DAH is diluted and likely to refocus on fragile states and global public goods with benefits to all countries (see below).As a result, member-state organizations like WHO and the World Bank, in coordination with other influential public and private actors, have new opportunities to address existing and emerging health challenges. 31Many existing organizations at the global and national level will adjust the role they play and how they fund their work in this new world health era.

Domestic Resource Mobilization
With emerging economies growing, the Third International Conference on Financing for Development, held in Addis Ababa, Ethiopia,  Good technical and political leadership is needed to address the underlying economic inequalities responsible for the social turmoil seen in many countries.
Health spending accounts for an expanding fraction of total spending for any growing economy.
positioned DRM at the heart of the post-2015 agenda. 32The World Bank estimates that simply bringing laggards to the median government revenue level by increasing tax ratios to the median 23% of GDP in low-and middleincome countries would add US$26 billion each year for public expenditure in health. 33In addition, increasing the government budget allocation for health to just the median level of 10% would generate an extra $50 billion each year. 33Tobacco taxes can contribute to general taxation and also reduce one of the main drivers for chronic diseases.Additional DRM possibilities include leveraging concessionary loans from development banks (e.g. the Global Financing Facility), 34 innovative financing (e.g., social impact bonds, loan guarantees), 35 and shaping responsible markets. 36Countries like Ghana, Ethiopia, and Rwanda have shown it is possible to increase health budgets significantly.

Universal Health Coverage
As shown in Figure 1, health spending is rising and will likely continue to do so as GDP expands.In the absence of government policy on public or private insurance, health spending is often paid out-of-pocket by individuals, which sends millions of families back into poverty. 37,38Such expenditures account for 50% of total health spending in most African countries and up to 80% in large South Asian nations-versus less than 20% in most countries of the Organisation for Economic Co-operation and Development (OECD). 11In response to this growing challenge, UHC is becoming the organizing principle for health systems everywhere. 39,40HC means 3 things: (1) access for all to (2) appropriate health services (at a minimum, health promotion and primary care, with additional services depending on local epidemiology and economics), and (3) without financial hardship (financial hardship is defined as 25% or more of total household expenditures spent on out-of-pocket health expenditures). 37UHC is not about donors buying health insurance but about national governments organizing health financing in equitable, prepaid risk pools. 32The services covered under UHC should be not only curative but also public health and preventive, like immunization, nutrition, family planning, and road safety interventions.Indeed a major challenge is to prioritize such services in the face of huge demand for expensive tertiary care for urban elites.According to the International Labour Organization, over 60 countries have achieved UHC and several more are halfway in their decades-long reforms (Figure 3). 41Many countries, especially in Africa, are asking for technical assistance to reorient their health sector toward UHC.
A global movement toward the progressive realization of UHC is unfolding. 37,42Following the World Health Report 2010, 37 the United Nations (UN) General Assembly passed a resolution supporting UHC, 43 which is now enshrined in the Sustainable Development Goal (SDG) targets for 2030. 44The G7 and the G20-the international Universal health coverage means access for all to appropriate health services without financial hardship.
summits where leaders from the world's advanced and emerging economies meet to discuss critical issues-support UHC, and a UHC Alliance has been born to foster and track progress to 2030.At the December 2017 Universal Health Coverage Forum in Tokyo, Japan's Prime Minister Shinzo Abe pledged US$2.9 billion for UHC while UN Secretary-General António Guterres announced UHC will be the subject of a high-level meeting at the UN General Assembly in 2019, 45 giving impetus to WHO's goal of expanding health coverage to an additional 1 billion people in 5 years. 37

Development Assistance for Health
This new world health era will be driven by DRM rather than DAH and that will affect the role played by governments, industry, and international organizations. 46Diluted by domestic growth, DAH today accounts for less than 20% of the total health spending even in Africa 47 and is shrinking in most recipient countries.It is already below 1% in middle-income countries like India.Donors are graduating successful countries from external assistance, 48 with the goal of concentrating DAH in the poorest nations by 2030. 40These international donors also have a window of opportunity to support the transformation of health systems toward prioritizing prevention and primary care in UHC; most DAH programs are moving from service provision to capacity building and technical assistance. 48

Global Public Goods
In this context, DAH should shift progressively to support global public goods 49   security, international norms, pooled procurement, and research development (particularly on diseases of poverty).While the Ebola epidemic galvanized donors to improve global health security, [50][51][52] the other areas mentioned deserve equal and sustained attention.Funding global public goods makes sense as DAH dollars in countries decline or are diluted by DRM, and given their broader benefits including to the citizens of donor countries.Led by BRICS countries (Brazil, Russia, India, China, and South Africa), these and many other "emerging" economies are also contributing valuable research and development and other innovations in South-South collaboration. 53he MDGs helped generate increased political support and funding against child and maternal mortality, HIV/AIDS, tuberculosis, and malaria.The end result was major reductions in mortality and suffering from these conditions. 2 However, chronic noncommunicable diseases (NCDs) are a neglected area in global health that is ripe for creative action.NCDs are now the leading cause of death worldwide, 54 and the epidemiologic transition is proceeding rapidly in Africa. 55Yet investments and effective solutions have lagged. 1,56HC, backed by targeted DAH, offers an opportunity to tackle NCDs with multisectoral initiatives as predicated by the SDG framework. 57e Private Sector and Civil Society During the 1970s, the private sector was nearly absent from public health circles, though it was already playing a growing role in the provision of medicines and clinical services.At the turn of the millennium, many public-private partnerships  PPPs 2.0 will be less top-down and more engaged in local markets and political economy, where the private sector accounts for half of total health expenditures. 1Private practitioners, formal or informal, already play a prominent role in service provision. 58Governments will need stronger stewardship capacity to regulate mixed health systems 59 and shape markets to ensure quality and equity. 31As countries move toward UHC, governments will need to prioritize public financing for primary health care and population-based prevention, besides provision of curative services. 60ivil society, uniting forces with public health officials and political leaders, dramatically changed the response to HIV/AIDS, making it a top priority at all levels and driving unprecedented growth of DAH for lifesaving interventions. 61Civil society organizations will continue to play a critical role even as some authoritarian governments try to close the space for their work.If anything, the moral and innovative voice of NGOs, community organizations, and other civil society actors is a public good that will further grow in importance to guide multisectoral policy for UHC and to hold politicians accountable to the citizenry. 62hile health is only one of 17 SDGs, the principle of partnership and new approaches to multisectoral collaboration will remain key in this new era.Interdependence requires closer cooperation and common aims among relevant UN agencies, development banks, professional organizations and, yes, the private sector.WHO governing bodies are exploring more inclusive engagement of non-state actors without compromising their ethics and neutrality. 63e World Health Organization As the premier UN agency for health, WHO figures prominently in historical analyses of international health. 14,22With greater emphasis on domestic resources, assertive member states, and the centrality of national health systems, this new era offers an opportunity to better define the role of intergovernmental organizations such as WHO and the World Bank. 64That is a challenge for the recently elected WHO Director-General 65 given the complexity the international arena accrued in the previous era 18 and the internal organizational challenges posed by decentralized management and constrained budgets 66 relative to expectations.Tellingly, the new Director-General is from Africa and was elected for the first time by all member states, giving him, in principle, unprecedented political capital to forge ahead with his priorities, including UHC and global health security.Unlike previous eras, this new agenda has been forged and embraced by the World Bank Group as central to human capital and economic development. 44o succeed in a new world health era and deliver on the SDG agenda, WHO will need to act on several fronts and focus on its comparative advantages.Firstly, while technical assistance to countries and strategic leadership may not be unique to WHO, ensuring their adequate and neutral provision to member states is key to its mission.WHO needs to be able to swiftly declare public health emergencies of international concern and help improve the world's capacity to detect and respond to pandemic threats, including adherence to international health regulations and new ideas like the Coalition for Epidemic Preparedness Innovations, 67 the Pandemic Emergency Financing Facility, 51 and the Global Virome Project. 68WHO will have a crucial role in rethinking and modernizing surveillance systems and data analytics platforms, as well as the standards, prequalification, and procurement of essential drugs and vaccines in collaboration with the private sector.
As with the Framework Convention on Tobacco Control and The World Health Report on UHC, 37 WHO will be expected to provide country guidance for future-oriented health systems and policies.Together with the World Bank and development partners, WHO should advocate for increasing DAH for the poorest countries while advising better-off members states to prepare for successful graduation from DAH through hybrid mechanisms like the Global Fund and the Global Financing Facility. 34Finally, WHO should expand the reach and quality of its advocacy and strategic communication capacity to ensure that global guidelines are clearly understood by all relevant audiences.
Internally, WHO needs to address several challenges if it is to thrive in this new world health era.It needs to define better the roles and responsibilities of its headquarters, regional, and country offices.Instead of relying only on its staff, WHO could harness today's global brain trust of experts and centers of excellence, and it should streamline the appointment of senior staff based on high-level PPPs 2.0 will be less top-down and more engaged in local markets and political economy.
WHO needs to address several internal challenges if it is to thrive in this new world health era.
expertise and competence rather than on geopolitical considerations.A major challenge compromising the of WHO and threatening its independence is its budget, 66 which is lower than the revenues of any large hospital in New York City-and three-quarters of the WHO budget comes from voluntary contributions.Member states' decisions to cut or increase assessed contributions will be pivotal.Finally, WHO needs to work well with the World Bank and related institutions, which can play a constructive role in financing health and development.

CONCLUSIONS
The priorities and approaches used in international health have evolved with epidemiological transitions and technological innovations.But the field has also been shaped by unprecedented economic development and a historical pendulum in the role of government in social well-being.Like the Soviet Union collapse in 1991, the Great Recession of 2008 triggered one such shift in the political economy between government and market.
Global health is moving past its stage of development assistance to a new era of country ownership and global cooperation. 69At the national level, the economic transition of health and growing political demands for social protection create conditions favorable for domestic resource mobilization and universal health coverage with new forms of private-sector engagement.At the global level, development assistance is refocused on fragile states, the poorest communities, and global public goods like health security, normativity, and innovation.
National health systems will be the center of gravity of a new world health era, and the evolving developments discussed in this article will call for adjustments in the fluid architecture of international actors and the relations within and between nation-states.This new era brings opportunities (e.g., UHC) and challenges (e.g., growing inequalities) and new ways of financing health.Leaders at all levels should understand and capitalize on this historical moment and avoid political miscalculations like those that undermined the visionary primary health care movement 40 years ago. 15,70

FIGURE 2 .
FIGURE 2. A New Chapter in International Health History

FIGURE 3 .
FIGURE 3. Universal Health Coverage a : The New Frontier for Global Health

41 (
PPPs), like Gavi or the Global Alliance for TB Drug Development, were created to market failures in the development and supply of drugs and vaccines.The change brought energy, creativity, and progress for orphan drugs and the MDGs.

TABLE .
Changes in the Health Field, 1960s to Present Day Abbreviations: DAH, development assistance for health; IT, information technology; MDGs, Millennium Development Goals; OECD, Organisation for Economic Co-operation and Development; PEPFAR, U.S. President's Emergency Plan for AIDS Relief; PPPs, public-private partnerships; SDGs, Sustainable Development Goals; UHC, universal health coverage; UN, United Nations; USAID, United States Agency for International Development; WHO, World Health Organization.